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Bioorganic & Medicinal Chemistry|June 23, 2012
Design, synthesis and antitumor activities of novel bis-aryl ureas derivatives as Raf kinase inhibitorsWenhu Zhan, Yanyang Li, Weiping Huang, et al.Journal of Medicinal Chemistry|January 6, 2023
Discovery of Highly Selective Inhibitors of the Human Constitutive Proteasome β5c Chymotryptic SubunitWenhu Zhan, Daqiang Li, Priya Saha, et al.Journal of Medicinal Chemistry|July 11, 2024
Directly Suppressing MYC Function with Novel Alkynyl-Substituted Phenylpyrazole Derivatives that Induce Protein Degradation and Perturb MYC/MAX InteractionCan Zhao, Fang Zhao, Liuqing Yang, et al.European Journal of Medicinal Chemistry|April 19, 2016
Design, synthesis and biological evaluation of pyrazol-furan carboxamide analogues as novel Akt kinase inhibitorsWenhu Zhan, Lei Xu, Xiaowu Dong, et al.Journal of Medicinal Chemistry|March 12, 2019
Phenotypic Screening-Based Identification of 3,4-Disubstituted Piperidine Derivatives as Macrophage M2 Polarization Modulators: An Opportunity for Treating Multiple SclerosisQinjie Weng, Jinxin Che, Zhikang Zhang, et al.Journal of Medicinal Chemistry|August 10, 2021
Discovery of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous ToxicityJinxin Che, Xiaoyang Dai, Jian Gao, et al.Nature Communications|December 14, 2023
Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitorsHao-Chi Hsu, Daqiang Li, Wenhu Zhan, et al.Nature Communications|November 24, 2017
Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytesRuda de Luna Almeida Santos, Lin Bai, Pradeep K Singh, et al.Journal of Medicinal Chemistry|October 23, 2020
Structure-Activity Relationships of Noncovalent Immunoproteasome β5i-Selective DipeptidesWenhu Zhan, Pradeep K Singh, Yi Ban, et al.Journal of Medicinal Chemistry|July 13, 2019
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based DesignXiaowu Dong, Wenhu Zhan, Mengting Zhao, et al.Pageof 3