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Blood
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December 1, 2020
Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas
Scott Boiko, Theresa Proia, Maryann San Martin, et al.
Journal of Medicinal Chemistry
|
February 11, 2017
"Addition" and "Subtraction": Selectivity Design for Type II Maternal Embryonic Leucine Zipper Kinase Inhibitors
Xin Chen, John Giraldes, Elizabeth R Sprague, et al.
Cell
|
July 13, 2005
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1
Jason S Carroll, X Shirley Liu, Alexander S Brodsky, et al.
Haematologica
|
December 3, 2009
In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma
Enrique M Ocio, David Vilanova, Peter Atadja, et al.
Journal of Medicinal Chemistry
|
January 21, 2012
[1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding
Michael D Shultz, Christina A Kirby, Travis Stams, et al.
Bioorganic & Medicinal Chemistry
|
July 5, 2011
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors
Lewis Whitehead, Markus R Dobler, Branko Radetich, et al.
Cancer Research
|
April 22, 2014
Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling
Marie Schoumacher, Kristen E Hurov, Joseph Lehár, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 31, 2015
Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer
Oriol Arqués, Irene Chicote, Isabel Puig, et al.
Journal of Medicinal Chemistry
|
March 9, 2010
Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824)
Young Shin Cho, Lewis Whitehead, Jianke Li, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 9, 2019
AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells
Justin Cidado, Scott Boiko, Theresa Proia, et al.
Page
of 4
Search research articles
Search
Showing results (11-20 of 35) with videos related to
Sort By:
Page
of 4
Blood
|
December 1, 2020
Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas
Scott Boiko, Theresa Proia, Maryann San Martin, et al.
Journal of Medicinal Chemistry
|
February 11, 2017
"Addition" and "Subtraction": Selectivity Design for Type II Maternal Embryonic Leucine Zipper Kinase Inhibitors
Xin Chen, John Giraldes, Elizabeth R Sprague, et al.
Cell
|
July 13, 2005
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1
Jason S Carroll, X Shirley Liu, Alexander S Brodsky, et al.
Haematologica
|
December 3, 2009
In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma
Enrique M Ocio, David Vilanova, Peter Atadja, et al.
Journal of Medicinal Chemistry
|
January 21, 2012
[1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding
Michael D Shultz, Christina A Kirby, Travis Stams, et al.
Bioorganic & Medicinal Chemistry
|
July 5, 2011
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors
Lewis Whitehead, Markus R Dobler, Branko Radetich, et al.
Cancer Research
|
April 22, 2014
Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling
Marie Schoumacher, Kristen E Hurov, Joseph Lehár, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 31, 2015
Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer
Oriol Arqués, Irene Chicote, Isabel Puig, et al.
Journal of Medicinal Chemistry
|
March 9, 2010
Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824)
Young Shin Cho, Lewis Whitehead, Jianke Li, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 9, 2019
AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells
Justin Cidado, Scott Boiko, Theresa Proia, et al.
Page
of 4