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Journal of Medicinal Chemistry
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February 7, 2024
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
Joshua R Hummel, Kai-Jiong Xiao, Jeffrey C Yang, et al.
Plos One
|
April 22, 2020
INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models
Phillip C C Liu, Holly Koblish, Liangxing Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 22, 2007
From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis
Joseph B Santella, Daniel S Gardner, Wenqing Yao, et al.
ACS Medicinal Chemistry Letters
|
March 16, 2023
Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure-Guided Scaffold Repurposing Approach
Minh H Nguyen, Hai-Fen Ye, Yao Xu, et al.
Plos One
|
June 22, 2018
Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies
Holly Koblish, Yun-Long Li, Niu Shin, et al.
ACS Medicinal Chemistry Letters
|
June 18, 2025
Discovery of INCB126503 as a Potent and Selective FGFR2/3 Inhibitor
Minh H Nguyen, Anlai Wang, Lisa Truong, et al.
Journal of Medicinal Chemistry
|
November 10, 2022
Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3
Artem Shvartsbart, Jeremy J Roach, Michael R Witten, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 10, 2022
Discovery of 1'-(1-phenylcyclopropane-carbonyl)-3H-spiro[isobenzofuran-1,3'-pyrrolidin]-3-one as a novel steroid mimetic scaffold for the potent and tissue-specific inhibition of 11β-HSD1 using a scaffold-hopping approach
Colin Zhang, Meizhong Xu, Chunhong He, et al.
Journal of Medicinal Chemistry
|
May 27, 2026
Discovery of Dual A<sub>2A</sub>/A<sub>2B</sub> Adenosine Receptor Antagonist and Clinical Candidate INCB106385
Chao Qi, Matthew S McCammant, Yong Li, et al.
The Lancet Regional Health. Western Pacific
|
February 15, 2021
Antibody seroprevalence in the epicenter Wuhan, Hubei, and six selected provinces after containment of the first epidemic wave of COVID-19 in China
Zhongjie Li, Xuhua Guan, Naiying Mao, et al.
Page
of 11
Search research articles
Search
Showing results (91-100 of 110) with videos related to
Sort By:
Page
of 11
Journal of Medicinal Chemistry
|
February 7, 2024
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
Joshua R Hummel, Kai-Jiong Xiao, Jeffrey C Yang, et al.
Plos One
|
April 22, 2020
INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models
Phillip C C Liu, Holly Koblish, Liangxing Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 22, 2007
From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis
Joseph B Santella, Daniel S Gardner, Wenqing Yao, et al.
ACS Medicinal Chemistry Letters
|
March 16, 2023
Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure-Guided Scaffold Repurposing Approach
Minh H Nguyen, Hai-Fen Ye, Yao Xu, et al.
Plos One
|
June 22, 2018
Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies
Holly Koblish, Yun-Long Li, Niu Shin, et al.
ACS Medicinal Chemistry Letters
|
June 18, 2025
Discovery of INCB126503 as a Potent and Selective FGFR2/3 Inhibitor
Minh H Nguyen, Anlai Wang, Lisa Truong, et al.
Journal of Medicinal Chemistry
|
November 10, 2022
Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3
Artem Shvartsbart, Jeremy J Roach, Michael R Witten, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 10, 2022
Discovery of 1'-(1-phenylcyclopropane-carbonyl)-3H-spiro[isobenzofuran-1,3'-pyrrolidin]-3-one as a novel steroid mimetic scaffold for the potent and tissue-specific inhibition of 11β-HSD1 using a scaffold-hopping approach
Colin Zhang, Meizhong Xu, Chunhong He, et al.
Journal of Medicinal Chemistry
|
May 27, 2026
Discovery of Dual A<sub>2A</sub>/A<sub>2B</sub> Adenosine Receptor Antagonist and Clinical Candidate INCB106385
Chao Qi, Matthew S McCammant, Yong Li, et al.
The Lancet Regional Health. Western Pacific
|
February 15, 2021
Antibody seroprevalence in the epicenter Wuhan, Hubei, and six selected provinces after containment of the first epidemic wave of COVID-19 in China
Zhongjie Li, Xuhua Guan, Naiying Mao, et al.
Page
of 11