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Drug Discovery Today
|
May 24, 2022
The development of small-molecule inhibitors targeting hexokinase 2
Wenying Shan, Yan Zhou, Kin Yip Tam
Current Medicinal Chemistry
|
May 27, 2020
Convolutional Neural Network-based Virtual Screening
Wenying Shan, Xuanyi Li, Hequan Yao, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease
|
April 18, 2025
Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
Wenying Shan, Shao-Lin Zhang, Yehuda G Assaraf, et al.
European Journal of Medicinal Chemistry
|
March 15, 2026
AI-driven identification of a selective dual function inhibitor blocking HK2 activity and HK2-VDAC1 interaction displaying enhanced anticancer efficacy under hypoxia
Wenying Shan, Shao-Lin Zhang, Yehuda G Assaraf, et al.
Translational Oncology
|
January 22, 2026
NF-κB activation as a pro-survival signal from pharmacological inhibition of pyruvate dehydrogenase kinase 1 in non-small-cell lung carcinoma cell models
Quan Liu, Maoxin Ran, Wenying Shan, et al.
ADMET & DMPK
|
December 23, 2024
Targeting hexokinase 2 to enhance anticancer efficacy of trichosanthin in HeLa and SCC25 cell models
Yan Zhou, Maoxin Ran, Wenying Shan, et al.
Frontiers in Chemistry
|
November 6, 2023
GcForest-based compound-protein interaction prediction model and its application in discovering small-molecule drugs targeting CD47
Wenying Shan, Lvqi Chen, Hao Xu, et al.
Phytotherapy Research : PTR
|
August 25, 2023
Epigallocatechin gallate circumvents drug-induced resistance in non-small-cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis
Yan Zhou, Shiqi Huang, Yizhen Guo, et al.
Chemico-Biological Interactions
|
April 2, 2023
Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models
Yizhen Guo, Yan Zhou, Puhua Wu, et al.
Biochemical Pharmacology
|
June 26, 2025
Benserazide‑mediated targeting hexokinase 2 enhances the cytotoxicity of cisplatin in non-small cell lung cancer cell models
Kaifang Wang, Suya Wang, Wenying Shan, et al.
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of 2
Search research articles
Search
Showing results (1-10 of 12) with videos related to
Sort By:
Page
of 2
Drug Discovery Today
|
May 24, 2022
The development of small-molecule inhibitors targeting hexokinase 2
Wenying Shan, Yan Zhou, Kin Yip Tam
Current Medicinal Chemistry
|
May 27, 2020
Convolutional Neural Network-based Virtual Screening
Wenying Shan, Xuanyi Li, Hequan Yao, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease
|
April 18, 2025
Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
Wenying Shan, Shao-Lin Zhang, Yehuda G Assaraf, et al.
European Journal of Medicinal Chemistry
|
March 15, 2026
AI-driven identification of a selective dual function inhibitor blocking HK2 activity and HK2-VDAC1 interaction displaying enhanced anticancer efficacy under hypoxia
Wenying Shan, Shao-Lin Zhang, Yehuda G Assaraf, et al.
Translational Oncology
|
January 22, 2026
NF-κB activation as a pro-survival signal from pharmacological inhibition of pyruvate dehydrogenase kinase 1 in non-small-cell lung carcinoma cell models
Quan Liu, Maoxin Ran, Wenying Shan, et al.
ADMET & DMPK
|
December 23, 2024
Targeting hexokinase 2 to enhance anticancer efficacy of trichosanthin in HeLa and SCC25 cell models
Yan Zhou, Maoxin Ran, Wenying Shan, et al.
Frontiers in Chemistry
|
November 6, 2023
GcForest-based compound-protein interaction prediction model and its application in discovering small-molecule drugs targeting CD47
Wenying Shan, Lvqi Chen, Hao Xu, et al.
Phytotherapy Research : PTR
|
August 25, 2023
Epigallocatechin gallate circumvents drug-induced resistance in non-small-cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis
Yan Zhou, Shiqi Huang, Yizhen Guo, et al.
Chemico-Biological Interactions
|
April 2, 2023
Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models
Yizhen Guo, Yan Zhou, Puhua Wu, et al.
Biochemical Pharmacology
|
June 26, 2025
Benserazide‑mediated targeting hexokinase 2 enhances the cytotoxicity of cisplatin in non-small cell lung cancer cell models
Kaifang Wang, Suya Wang, Wenying Shan, et al.
Page
of 2