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Nucleic Acids Research|July 5, 2020
DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analysesHao Yu, Jiayi Li, Guang Liu, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|May 22, 2021
Liver Toxicity Observed With Lorlatinib When Combined With Strong CYP3A Inducers: Evaluation of Cynomolgus Monkey as a Nonclinical Model for Assessing the Mechanism of Combinational ToxicityWenyue Hu, Daniel Lettiere, Susanna Tse, et al.
Toxicologic Pathology|December 27, 2016
Evaluation of miR-216a and miR-217 as Potential Biomarkers of Acute Exocrine Pancreatic Toxicity in RatsJianying Wang, Wenhu Huang, Stephane Thibault, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|April 10, 2024
Deciphering mitochondrial dysfunction: Pathophysiological mechanisms in vascular cognitive impairmentYuyao He, Tiantian He, Hongpei Li, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|March 27, 2007
Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicityMatthew T Martin, Richard J Brennan, Wenyue Hu, et al.
Toxicology and Applied Pharmacology|February 12, 2024
Translation of nonclinical to clinical safety findings for 27 biotherapeuticsMichael W Leach, Payal Rana, Wenyue Hu, et al.
Nature Reviews. Drug Discovery|May 2, 2025
Application of new approach methodologies for nonclinical safety assessment of drug candidatesMario Beilmann, Karissa Adkins, Harrie C M Boonen, et al.
Molecular Cancer Therapeutics|July 4, 2012
Epithelial tissue hyperplasia induced by the RAF inhibitor PF-04880594 is attenuated by a clinically well-tolerated dose of the MEK inhibitor PD-0325901Vince R Torti, Donald Wojciechowicz, Wenyue Hu, et al.
Molecular Cancer Therapeutics|August 7, 2016
Spectrum and Degree of CDK Drug Interactions Predicts Clinical PerformancePing Chen, Nathan V Lee, Wenyue Hu, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|January 26, 2020
An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological ToxicityYik Andy Yeung, Veena Krishnamoorthy, Danielle Dettling, et al.
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