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Chemmedchem|November 13, 2007
Metabolite identification via LC-SPE-NMR-MS of the in vitro biooxidation products of a lead mGlu5 allosteric antagonist and impact on the improvement of metabolic stability in the seriesSimona M Ceccarelli, Götz Schlotterbeck, Patrick Boissin, et al.
Autism Research : Official Journal of the International Society for Autism Research|February 12, 2019
Investigating the factors underlying adaptive functioning in autism in the EU-AIMS Longitudinal European Autism ProjectJulian Tillmann, Antonia San José Cáceres, Chris H Chatham, et al.
Scientific Reports|August 14, 2019
Reproducibility via coordinated standardization: a multi-center study in a Shank2 genetic rat model for Autism Spectrum DisordersMaría Arroyo-Araujo, Radka Graf, Martine Maco, et al.
Biological Psychiatry. Cognitive Neuroscience and Neuroimaging|February 4, 2019
Altered Connectivity Between Cerebellum, Visual, and Sensory-Motor Networks in Autism Spectrum Disorder: Results from the EU-AIMS Longitudinal European Autism ProjectMarianne Oldehinkel, Maarten Mennes, Andre Marquand, et al.
Nature Reviews. Drug Discovery|December 9, 2017
Drug development for neurodevelopmental disorders: lessons learned from fragile X syndromeElizabeth M Berry-Kravis, Lothar Lindemann, Aia E Jønch, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 11, 2015
Pharmacology of basimglurant (RO4917523, RG7090), a unique metabotropic glutamate receptor 5 negative allosteric modulator in clinical development for depressionLothar Lindemann, Richard H Porter, Sebastian H Scharf, et al.
Molecular Autism|February 24, 2020
Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism ProjectCarolin Moessnang, Sarah Baumeister, Julian Tillmann, et al.
Journal of Medicinal Chemistry|January 8, 2015
Metabotropic glutamate receptor 5 negative allosteric modulators: discovery of 2-chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]pyridine (basimglurant, RO4917523), a promising novel medicine for psychiatric diseasesGeorg Jaeschke, Sabine Kolczewski, Will Spooren, et al.
Science Translational Medicine|March 1, 2019
Patients with autism spectrum disorders display reproducible functional connectivity alterationsŠtefan Holiga, Joerg F Hipp, Christopher H Chatham, et al.
Communications Biology|May 15, 2021
Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitryNatasha Bertelsen, Isotta Landi, Richard A I Bethlehem, et al.
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