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Genes & Diseases|April 1, 2024
CYP3A5 unexpectedly regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancerMing Shao, Qingfei Pan, Haiyan Tan, et al.
Biochemical Pharmacology|April 3, 2018
CINPA1 binds directly to constitutive androstane receptor and inhibits its activityMilu T Cherian, Sergio C Chai, William C Wright, et al.
BMC Cancer|March 23, 2019
Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cellsJesse Bakke, William C Wright, Anthony E Zamora, et al.
Journal of Medicinal Chemistry|January 23, 2020
Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5William C Wright, Jude Chenge, Jingheng Wang, et al.
Journal of the American Chemical Society|October 14, 2021
Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5Jingheng Wang, Cameron D Buchman, Jayaraman Seetharaman, et al.
Nature Communications|December 15, 2025
An open-source screening platform accelerates discovery of drug combinationsWilliam C Wright, Min Pan, Gregory A Phelps, et al.
Nucleic Acids Research|February 25, 2022
Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulationMonicah N Bwayi, Efren Garcia-Maldonado, Sergio C Chai, et al.
Biorxiv : the Preprint Server for Biology|February 20, 2025
Receptor Allostery Promotes Context-Dependent Sonic Hedgehog Signaling During Embryonic DevelopmentShariq S Ansari, Miriam E Dillard, Mohamed Ghonim, et al.
Nature Communications|November 13, 2023
A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeuticsHyeong-Min Lee, William C Wright, Min Pan, et al.
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