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Neuro-Oncology|March 12, 2026
Evaluating "Brain Permeability": A Critical Issue for the Development of Therapeutic Agents for Primary and Metastatic Brain TumorsStuart A Grossman, Amy Barone, Roy E Strowd, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 14, 2024
Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma ModelsSonia Jain, Jessica I Griffith, Kendra A Porath, et al.
Neuro-Oncology|September 26, 2015
CNS Anticancer Drug Discovery and Development Conference White PaperVictor A Levin, Peter J Tonge, James M Gallo, et al.
Molecular Cancer Therapeutics|January 15, 2024
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis XenograftsJianxiong Ji, Sonja Dragojevic, Cameron M Callaghan, et al.
Neuro-Oncology Advances|February 10, 2026
Pharmacokinetic-pharmacodynamic-efficacy modeling of the MDM2 inhibitor brigimadlin in glioblastoma patient-derived xenograftsRachael A Vaubel, Wenjuan Zhang, Nishika Karbhari, et al.
Neuro-Oncology Advances|June 16, 2023
WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse modelsJason E Conage-Pough, Sylwia A Stopka, Ju-Hee Oh, et al.
Molecular Cancer Therapeutics|July 5, 2018
Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood-Brain BarrierMinjee Kim, Daniel J Ma, David Calligaris, et al.
Investigational New Drugs|September 29, 2018
E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastasesHani M Babiker, Sara A Byron, William P D Hendricks, et al.
Pharmaceutical Research|April 27, 2007
AAPS-FDA workshop white paper: microdialysis principles, application and regulatory perspectivesChandra S Chaurasia, Markus Müller, Edward D Bashaw, et al.
Neuro-Oncology|April 15, 2025
The novel brain penetrant ATM inhibitor WSD0628 provides robust radiosensitization of brain tumor patient derived xenograftsZhiyi Xue, Ann C Mladek, Sneha Rathi, et al.
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