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William Farnaby

Showing results (11-20 of 21) with videos related to

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Nature Communications|October 6, 2025
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screeningAndreas Holmqvist, Nur Mehpare Kocaturk, Christina Duncan, et al.
Scientific Reports|October 14, 2020
Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in miceToshiya Nishi, Shinichi Kondo, Maki Miyamoto, et al.
Nature Communications|September 29, 2025
Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexesNing Ma, Supriyo Bhattacharya, Sanychen Muk, et al.
ACS Medicinal Chemistry Letters|February 19, 2025
Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant LinkersAndrew McGown, Vesna Vetma, Damien Crepin, et al.
Nature Communications|October 15, 2024
Design of a Cereblon construct for crystallographic and biophysical studies of protein degradersAlena Kroupova, Valentina A Spiteri, Zoe J Rutter, et al.
Journal of the American Chemical Society|October 30, 2025
Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-Loaded KRAS(On) AllelesVesna Vetma, Ilaria Puoti, Natalia K Karolak, et al.
ACS Chemical Biology|July 3, 2024
Confounding Factors in Targeted Degradation of Short-Lived ProteinsVesna Vetma, Laura Casares Perez, Ján Eliaš, et al.
Nature Communications|October 10, 2022
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivoChristiane Kofink, Nicole Trainor, Barbara Mair, et al.
Nature Chemical Biology|June 11, 2019
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC designWilliam Farnaby, Manfred Koegl, Michael J Roy, et al.
Nature Chemical Biology|July 4, 2019
Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC designWilliam Farnaby, Manfred Koegl, Michael J Roy, et al.
Pageof 3

Showing results (11-20 of 21) with videos related to

Sort By:
Pageof 3
Nature Communications|October 6, 2025
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screeningAndreas Holmqvist, Nur Mehpare Kocaturk, Christina Duncan, et al.
Scientific Reports|October 14, 2020
Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in miceToshiya Nishi, Shinichi Kondo, Maki Miyamoto, et al.
Nature Communications|September 29, 2025
Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexesNing Ma, Supriyo Bhattacharya, Sanychen Muk, et al.
ACS Medicinal Chemistry Letters|February 19, 2025
Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant LinkersAndrew McGown, Vesna Vetma, Damien Crepin, et al.
Nature Communications|October 15, 2024
Design of a Cereblon construct for crystallographic and biophysical studies of protein degradersAlena Kroupova, Valentina A Spiteri, Zoe J Rutter, et al.
Journal of the American Chemical Society|October 30, 2025
Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-Loaded KRAS(On) AllelesVesna Vetma, Ilaria Puoti, Natalia K Karolak, et al.
ACS Chemical Biology|July 3, 2024
Confounding Factors in Targeted Degradation of Short-Lived ProteinsVesna Vetma, Laura Casares Perez, Ján Eliaš, et al.
Nature Communications|October 10, 2022
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivoChristiane Kofink, Nicole Trainor, Barbara Mair, et al.
Nature Chemical Biology|June 11, 2019
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC designWilliam Farnaby, Manfred Koegl, Michael J Roy, et al.
Nature Chemical Biology|July 4, 2019
Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC designWilliam Farnaby, Manfred Koegl, Michael J Roy, et al.
Pageof 3