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Antimicrobial Agents and Chemotherapy|January 21, 2016
The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattiiShawn R Lockhart, Annette W Fothergill, Naureen Iqbal, et al.Journal of Medicinal Chemistry|March 18, 2005
Discovery of novel quinoline-based estrogen receptor ligands using peptide interaction profilingWilliam J Hoekstra, Hari S Patel, Xi Liang, et al.Bioorganic & Medicinal Chemistry Letters|March 18, 2003
Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonistsJay M Matthews, Michael N Greco, Leonard R Hecker, et al.Antimicrobial Agents and Chemotherapy|December 9, 2015
Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruziWilliam J Hoekstra, Tatiana Y Hargrove, Zdzislaw Wawrzak, et al.Antimicrobial Agents and Chemotherapy|September 16, 2015
Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection ModelsLisa F Shubitz, Hien T Trinh, John N Galgiani, et al.Bioorganic & Medicinal Chemistry Letters|May 30, 2007
Co-crystal structure guided array synthesis of PPARgamma inverse agonistsRyan P Trump, Jeffrey E Cobb, Barry G Shearer, et al.Antimicrobial Agents and Chemotherapy|July 11, 2018
The Fungal Cyp51 Inhibitor VT-1129 Is Efficacious in an Experimental Model of Cryptococcal MeningitisNathan P Wiederhold, Laura K Najvar, Edward P Garvey, et al.Antimicrobial Agents and Chemotherapy|August 15, 2018
<i>In Vivo</i> Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration StrategyNathan P Wiederhold, Xin Xu, Amy Wang, et al.Bioorganic & Medicinal Chemistry Letters|September 24, 2004
Piperidine-containing beta-arylpropionic acids as potent antagonists of alphavbeta3/alphavbeta5 integrinsBart L De Corte, William A Kinney, Li Liu, et al.Bioorganic & Medicinal Chemistry Letters|May 6, 2004
Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templatesJay M Matthews, William J Hoekstra, Alexey B Dyatkin, et al.Pageof 4