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Angewandte Chemie (International Ed. in English)
|
October 30, 2024
Selective Deuteration and Tritiation of Pharmaceutically Relevant Sulfoximines
Blair I P Smith, Nathan M L Knight, Gary J Knox, et al.
ACS Chemical Biology
|
February 27, 2019
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding
Christopher P Tinworth, Hannah Lithgow, Lars Dittus, et al.
The Journal of Biological Chemistry
|
August 13, 2013
Discovery of novel irreversible inhibitors of interleukin (IL)-2-inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket
John D Harling, Angela M Deakin, Sébastien Campos, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 21, 2018
Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase
David H McGarry, Ian R Cooper, Rolf Walker, et al.
Journal of Medicinal Chemistry
|
November 15, 2023
Structure-Guided Design of a Domain-Selective Bromodomain and Extra Terminal N-Terminal Bromodomain Chemical Probe
Erin Bradley, Lucia Fusani, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry
|
May 4, 2026
Targeting Activin Receptor-like Kinase 2 Using Heterobifunctional Protein Degraders
Daniel T Webb, Katherine L Jones, Natsuko Macabuag, et al.
Journal of Medicinal Chemistry
|
August 6, 2019
Profile of a Highly Selective Quaternized Pyrrolidine Betaine α<sub>v</sub>β<sub>6</sub> Integrin Inhibitor-(3<i>S</i>)-3-(3-(3,5-Dimethyl-1<i>H</i>-pyrazol-1-yl)phenyl)-4-((1<i>S</i> and 1<i>R</i>,3<i>R</i>)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective Methylation
Tim N Barrett, Jonathan A Taylor, Daniel Barker, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Structure-Based Design of a Bromodomain and Extraterminal Domain (BET) Inhibitor Selective for the N-Terminal Bromodomains That Retains an Anti-inflammatory and Antiproliferative Phenotype
Christopher R Wellaway, Paul Bamborough, Sharon G Bernard, et al.
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Showing results (51-60 of 58) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 58 results.
Angewandte Chemie (International Ed. in English)
|
October 30, 2024
Selective Deuteration and Tritiation of Pharmaceutically Relevant Sulfoximines
Blair I P Smith, Nathan M L Knight, Gary J Knox, et al.
ACS Chemical Biology
|
February 27, 2019
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding
Christopher P Tinworth, Hannah Lithgow, Lars Dittus, et al.
The Journal of Biological Chemistry
|
August 13, 2013
Discovery of novel irreversible inhibitors of interleukin (IL)-2-inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket
John D Harling, Angela M Deakin, Sébastien Campos, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 21, 2018
Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase
David H McGarry, Ian R Cooper, Rolf Walker, et al.
Journal of Medicinal Chemistry
|
November 15, 2023
Structure-Guided Design of a Domain-Selective Bromodomain and Extra Terminal N-Terminal Bromodomain Chemical Probe
Erin Bradley, Lucia Fusani, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry
|
May 4, 2026
Targeting Activin Receptor-like Kinase 2 Using Heterobifunctional Protein Degraders
Daniel T Webb, Katherine L Jones, Natsuko Macabuag, et al.
Journal of Medicinal Chemistry
|
August 6, 2019
Profile of a Highly Selective Quaternized Pyrrolidine Betaine α<sub>v</sub>β<sub>6</sub> Integrin Inhibitor-(3<i>S</i>)-3-(3-(3,5-Dimethyl-1<i>H</i>-pyrazol-1-yl)phenyl)-4-((1<i>S</i> and 1<i>R</i>,3<i>R</i>)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective Methylation
Tim N Barrett, Jonathan A Taylor, Daniel Barker, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Structure-Based Design of a Bromodomain and Extraterminal Domain (BET) Inhibitor Selective for the N-Terminal Bromodomains That Retains an Anti-inflammatory and Antiproliferative Phenotype
Christopher R Wellaway, Paul Bamborough, Sharon G Bernard, et al.
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of 6