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Nature Reviews. Cancer|May 25, 2011
Targeting hypoxia in cancer therapyWilliam R Wilson, Michael P HayBioorganic & Medicinal Chemistry|May 25, 2005
Nitroarylmethylcarbamate prodrugs of doxorubicin for use with nitroreductase gene-directed enzyme prodrug therapyMichael P Hay, William R Wilson, William A DennyMolecules (Basel, Switzerland)|April 24, 2019
Studies Towards Hypoxia-Activated Prodrugs of PARP InhibitorsBenjamin D Dickson, Way Wua Wong, William R Wilson, et al.Journal of Medicinal Chemistry|May 30, 2003
Structure-activity relationships for 4-nitrobenzyl carbamates of 5-aminobenz[e]indoline minor groove alkylating agents as prodrugs for GDEPT in conjunction with E. coli nitroreductaseMichael P Hay, Graham J Atwell, William R Wilson, et al.Journal of Medicinal Chemistry|December 4, 2003
Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapyMichael P Hay, Robert F Anderson, Dianne M Ferry, et al.Journal of Pharmaceutical Sciences|September 13, 2014
Photodegradation of the benzotriazine 1,4-Di-N-oxide hypoxia-activated prodrug SN30000 in aqueous solutionYongchuan Gu, Jagdish K Jaiswal, Jingli Wang, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 15, 2011
The 2-nitroimidazole EF5 is a biomarker for oxidoreductases that activate the bioreductive prodrug CEN-209 under hypoxiaJingli Wang, Annika Foehrenbacher, Jiechuang Su, et al.Journal of Medicinal Chemistry|February 18, 2005
Extravascular transport of drugs in tumor tissue: effect of lipophilicity on diffusion of tirapazamine analogues in multicellular layer culturesFrederik B Pruijn, Joanna R Sturman, H D Sarath Liyanage, et al.RSC Medicinal Chemistry|July 24, 2023
Hypoxia-activated prodrugs of phenolic olaparib analogues for tumour-selective chemosensitisationWay W Wong, Sophia F O'Brien-Gortner, Robert F Anderson, et al.Journal of Medicinal Chemistry|November 16, 2007
Pharmacokinetic/pharmacodynamic model-guided identification of hypoxia-selective 1,2,4-benzotriazine 1,4-dioxides with antitumor activity: the role of extravascular transportMichael P Hay, Kevin O Hicks, Frederik B Pruijn, et al.Pageof 16