Showing results (21-30 of 154) with videos related to
Sort By:
Pageof 16
Journal of the National Cancer Institute|August 17, 2006
Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugsKevin O Hicks, Frederik B Pruijn, Timothy W Secomb, et al.Journal of Medicinal Chemistry|December 28, 2002
Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamineMichael P Hay, Swarna A Gamage, Mary S Kovacs, et al.Molecules (Basel, Switzerland)|July 13, 2019
Benzotriazine Di-Oxide Prodrugs for Exploiting Hypoxia and Low Extracellular pH in TumorsMichael P Hay, Hong Nam Shin, Way Wua Wong, et al.Journal of Medicinal Chemistry|December 7, 2007
Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activityMichael P Hay, Karin Pchalek, Frederik B Pruijn, et al.Journal of Medicinal Chemistry|October 14, 2008
Tricyclic [1,2,4]triazine 1,4-dioxides as hypoxia selective cytotoxinsMichael P Hay, Kevin O Hicks, Karin Pchalek, et al.Biochemical Pharmacology|September 22, 2019
Hypoxia-selective radiosensitisation by SN38023, a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361Way Wua Wong, Rosanna K Jackson, Lydia P Liew, et al.Journal of Medicinal Chemistry|January 9, 2004
DNA-targeted 1,2,4-benzotriazine 1,4-dioxides: potent analogues of the hypoxia-selective cytotoxin tirapazamineMichael P Hay, Frederik B Pruijn, Swarna A Gamage, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|August 28, 2009
Rapid and sensitive ultra-high-pressure liquid chromatography-tandem mass spectrometry analysis of the novel anticancer agent PR-104 and its major metabolites in human plasma: Application to a pharmacokinetic studyYongchuan Gu, William R WilsonAdvances in Experimental Medicine and Biology|November 26, 2013
Hypoxia-directed drug strategies to target the tumor microenvironmentMichael P Hay, Kevin O Hicks, Jingli WangJournal of Medicinal Chemistry|July 15, 2024
Identification of 6-Anilino Imidazo[4,5-c]pyridin-2-ones as Selective DNA-Dependent Protein Kinase Inhibitors and Their Application as RadiosensitizersCho R Hong, Lydia P Liew, Way W Wong, et al.Pageof 16