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Cancer Chemotherapy and Pharmacology
|
December 24, 2002
Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
Bronwyn G Siim, Alan E Lee, Sahar Shalal-Zwain, et al.
Plos Computational Biology
|
October 26, 2018
An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids
Xinjian Mao, Sarah McManaway, Jagdish K Jaiswal, et al.
Radiation Research
|
May 26, 2007
Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards
William R Wilson, Kevin O Hicks, Susan M Pullen, et al.
BMC Cancer
|
October 11, 2011
A phase I trial of PR-104, a pre-prodrug of the bioreductive prodrug PR-104A, given weekly to solid tumour patients
Mark J McKeage, Yongchuan Gu, William R Wilson, et al.
International Journal of Radiation Oncology, Biology, Physics
|
September 18, 2007
Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamine
Kevin O Hicks, Hilary Myint, Adam V Patterson, et al.
RSC Medicinal Chemistry
|
July 24, 2023
Hypoxia-activated prodrugs of phenolic olaparib analogues for tumour-selective chemosensitisation
Way W Wong, Sophia F O'Brien-Gortner, Robert F Anderson, et al.
Bioorganic & Medicinal Chemistry
|
July 20, 2011
The effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins
Amir Ashoorzadeh, Graham J Atwell, Frederik B Pruijn, et al.
The Journal of Biological Chemistry
|
November 8, 2013
Zinc finger nuclease knock-out of NADPH:cytochrome P450 oxidoreductase (POR) in human tumor cell lines demonstrates that hypoxia-activated prodrugs differ in POR dependence
Jiechuang Su, Yongchuan Gu, Frederik B Pruijn, et al.
Journal of Medicinal Chemistry
|
February 18, 2005
Extravascular transport of drugs in tumor tissue: effect of lipophilicity on diffusion of tirapazamine analogues in multicellular layer cultures
Frederik B Pruijn, Joanna R Sturman, H D Sarath Liyanage, et al.
Frontiers in Oncology
|
October 11, 2013
The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104
Annika Foehrenbacher, Kashyap Patel, Maria R Abbattista, et al.
Page
of 13
Search research articles
Search
Showing results (51-60 of 125) with videos related to
Sort By:
Page
of 13
Cancer Chemotherapy and Pharmacology
|
December 24, 2002
Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
Bronwyn G Siim, Alan E Lee, Sahar Shalal-Zwain, et al.
Plos Computational Biology
|
October 26, 2018
An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids
Xinjian Mao, Sarah McManaway, Jagdish K Jaiswal, et al.
Radiation Research
|
May 26, 2007
Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards
William R Wilson, Kevin O Hicks, Susan M Pullen, et al.
BMC Cancer
|
October 11, 2011
A phase I trial of PR-104, a pre-prodrug of the bioreductive prodrug PR-104A, given weekly to solid tumour patients
Mark J McKeage, Yongchuan Gu, William R Wilson, et al.
International Journal of Radiation Oncology, Biology, Physics
|
September 18, 2007
Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamine
Kevin O Hicks, Hilary Myint, Adam V Patterson, et al.
RSC Medicinal Chemistry
|
July 24, 2023
Hypoxia-activated prodrugs of phenolic olaparib analogues for tumour-selective chemosensitisation
Way W Wong, Sophia F O'Brien-Gortner, Robert F Anderson, et al.
Bioorganic & Medicinal Chemistry
|
July 20, 2011
The effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins
Amir Ashoorzadeh, Graham J Atwell, Frederik B Pruijn, et al.
The Journal of Biological Chemistry
|
November 8, 2013
Zinc finger nuclease knock-out of NADPH:cytochrome P450 oxidoreductase (POR) in human tumor cell lines demonstrates that hypoxia-activated prodrugs differ in POR dependence
Jiechuang Su, Yongchuan Gu, Frederik B Pruijn, et al.
Journal of Medicinal Chemistry
|
February 18, 2005
Extravascular transport of drugs in tumor tissue: effect of lipophilicity on diffusion of tirapazamine analogues in multicellular layer cultures
Frederik B Pruijn, Joanna R Sturman, H D Sarath Liyanage, et al.
Frontiers in Oncology
|
October 11, 2013
The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104
Annika Foehrenbacher, Kashyap Patel, Maria R Abbattista, et al.
Page
of 13