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Plos Medicine
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October 5, 2016
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling
Amélie Le Bihan, Ruben de Kanter, Iñigo Angulo-Barturen, et al.
Science (New York, N.Y.)
|
June 2, 2022
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
Stanley C Xie, Riley D Metcalfe, Elyse Dunn, et al.
Revista De Saude Publica
|
December 17, 2020
Population-based seroprevalence of SARS-CoV-2 and the herd immunity threshold in Maranhão
Antônio Augusto Moura da Silva, Lídio Gonçalves Lima-Neto, Conceição de Maria Pedrozo E Silva de Azevedo, et al.
Plos Pathogens
|
December 9, 2024
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
Stanley C Xie, Chia-Wei Tai, Craig J Morton, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
September 22, 2021
Design of proteasome inhibitors with oral efficacy in vivo against <i>Plasmodium falciparum</i> and selectivity over the human proteasome
Stanley C Xie, Riley D Metcalfe, Hirotake Mizutani, et al.
Journal of Medicinal Chemistry
|
October 10, 2022
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of <b>UCB7362</b>
Martin A Lowe, Alvaro Cardenas, Jean-Pierre Valentin, et al.
Journal of Medicinal Chemistry
|
April 20, 2021
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series
Michael J Palmer, Xiaoyi Deng, Shawn Watts, et al.
Journal of Medicinal Chemistry
|
February 12, 2021
Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite <i>Plasmodium falciparum</i> and Optimization Efforts
Claire Le Manach, Jean Dam, John G Woodland, et al.
Antimicrobial Agents and Chemotherapy
|
June 27, 2018
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria
Christel Brunschwig, Nina Lawrence, Dale Taylor, et al.
Nature Communications
|
April 21, 2022
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
Laura E de Vries, Patrick A M Jansen, Catalina Barcelo, et al.
Page
of 32
Search research articles
Search
Showing results (271-280 of 318) with videos related to
Sort By:
Page
of 32
Plos Medicine
|
October 5, 2016
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling
Amélie Le Bihan, Ruben de Kanter, Iñigo Angulo-Barturen, et al.
Science (New York, N.Y.)
|
June 2, 2022
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
Stanley C Xie, Riley D Metcalfe, Elyse Dunn, et al.
Revista De Saude Publica
|
December 17, 2020
Population-based seroprevalence of SARS-CoV-2 and the herd immunity threshold in Maranhão
Antônio Augusto Moura da Silva, Lídio Gonçalves Lima-Neto, Conceição de Maria Pedrozo E Silva de Azevedo, et al.
Plos Pathogens
|
December 9, 2024
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
Stanley C Xie, Chia-Wei Tai, Craig J Morton, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
September 22, 2021
Design of proteasome inhibitors with oral efficacy in vivo against <i>Plasmodium falciparum</i> and selectivity over the human proteasome
Stanley C Xie, Riley D Metcalfe, Hirotake Mizutani, et al.
Journal of Medicinal Chemistry
|
October 10, 2022
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of <b>UCB7362</b>
Martin A Lowe, Alvaro Cardenas, Jean-Pierre Valentin, et al.
Journal of Medicinal Chemistry
|
April 20, 2021
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series
Michael J Palmer, Xiaoyi Deng, Shawn Watts, et al.
Journal of Medicinal Chemistry
|
February 12, 2021
Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite <i>Plasmodium falciparum</i> and Optimization Efforts
Claire Le Manach, Jean Dam, John G Woodland, et al.
Antimicrobial Agents and Chemotherapy
|
June 27, 2018
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria
Christel Brunschwig, Nina Lawrence, Dale Taylor, et al.
Nature Communications
|
April 21, 2022
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
Laura E de Vries, Patrick A M Jansen, Catalina Barcelo, et al.
Page
of 32