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Oncogenesis|May 14, 2021
A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivoYi-Wen Wu, Min-Wu Chao, Huang-Ju Tu, et al.Scientific Reports|March 22, 2017
Several microRNAs could predict survival in patients with hepatitis B-related liver cancerYe Zhen, Zhao Xinghui, Wu Chao, et al.Scientific Reports|August 17, 2016
MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancerHan-Li Huang, Min-Wu Chao, Ya-Chi Li, et al.Clinical Epigenetics|December 31, 2018
The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cellsHuang-Ju Tu, Yi-Jyun Lin, Min-Wu Chao, et al.European Journal of Medicinal Chemistry|May 2, 2021
Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivoYi-Min Liu, Huang-Ju Tu, Chueh-Heng Wu, et al.Journal of Enzyme Inhibition and Medicinal Chemistry|December 13, 2021
Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitorsTony Eight Lin, Li-Chin Sung, Min-Wu Chao, et al.European Journal of Medicinal Chemistry|October 27, 2019
N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expressionSamir Mehndiratta, Mei-Hsiang Lin, Yi-Wen Wu, et al.Frontiers in Pharmacology|December 20, 2018
A Novel Selective JAK2 Inhibitor Identified Using Pharmacological InteractionsTony Eight Lin, Wei-Chun HuangFu, Min-Wu Chao, et al.Journal of Enzyme Inhibition and Medicinal Chemistry|November 4, 2024
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formationHuang-Ju Tu, Min-Wu Chao, Cheng-Chung Lee, et al.Scientific Reports|July 1, 2020
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitorsKai-Cheng Hsu, Wei-Chun HuangFu, Tony Eight Lin, et al.Pageof 8