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Journal of Medicinal Chemistry|April 16, 2019
Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved TolerabilityJoey L Methot, Hua Zhou, Sam D Kattar, et al.Molecular Cancer Therapeutics|April 14, 2007
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analoguesSwee Y Sharp, Chrisostomos Prodromou, Kathy Boxall, et al.Journal of Medicinal Chemistry|April 2, 2021
Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ ImmunomodulatorsJoey L Methot, Hua Zhou, Meredeth A McGowan, et al.ACS Medicinal Chemistry Letters|April 22, 2022
Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 InhibitorsChunhui Huang, Christian Fischer, Michelle R Machacek, et al.Bioorganic & Medicinal Chemistry Letters|June 24, 2021
SAR towards indoline and 3-azaindoline classes of IDO1 inhibitorsWensheng Yu, Yongqi Deng, Brett Hopkins, et al.Journal of Medicinal Chemistry|March 25, 2016
Identification and in Vivo Evaluation of Liver X Receptor β-Selective Agonists for the Potential Treatment of Alzheimer's DiseaseShawn J Stachel, Celina Zerbinatti, Michael T Rudd, et al.Journal of Medicinal Chemistry|October 29, 2021
Discovery of <b>MK-4688</b>: an Efficient Inhibitor of the HDM2-p53 Protein-Protein InteractionMichael H Reutershan, Michelle R Machacek, Michael D Altman, et al.Journal of Medicinal Chemistry|July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperonePaul A Brough, Xavier Barril, Jenifer Borgognoni, et al.Journal of Medicinal Chemistry|March 3, 2022
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral DosingDerun Li, David L Sloman, Abdelghani Achab, et al.ACS Medicinal Chemistry Letters|March 19, 2021
Carbamate and <i>N</i>-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 InhibitorsDerun Li, Yongqi Deng, Abdelghani Achab, et al.Pageof 13