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The Journal of Biological Chemistry|January 8, 2020
The bacterial deubiquitinase Ceg23 regulates the association of Lys-63-linked polyubiquitin molecules on the Legionella phagosomeKelong Ma, Xiangkai Zhen, Biao Zhou, et al.Nature Communications|January 10, 2024
Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA systemXiangkai Zhen, Xiaolong Xu, Le Ye, et al.Nature Communications|January 6, 2026
Filament assembly induced by the recognition of target DNA activates the prokaryotic Argonaute SPARDA systemWanyue Zhang, Yuchen Jiang, Yu Li, et al.Nature Communications|July 26, 2022
Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophilaXiangkai Zhen, Yongyu Wu, Jinli Ge, et al.Nucleic Acids Research|October 12, 2020
Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin systemJianyun Yao, Xiangkai Zhen, Kaihao Tang, et al.Nature Communications|October 28, 2024
Mechanistic basis for the allosteric activation of NADase activity in the Sir2-HerA antiphage defense systemXiangkai Zhen, Biao Zhou, Zihe Liu, et al.Molecular Cell|February 4, 2026
Filament-driven activation of the Kongming antiviral system by deoxyinosine triphosphateXiangkai Zhen, Yu Li, Zihe Liu, et al.Nature Communications|December 15, 2022
A secreted effector with a dual role as a toxin and as a transcriptional factorDandan Wang, Lingfang Zhu, Xiangkai Zhen, et al.Nature|July 23, 2019
Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylaseNinghai Gan, Xiangkai Zhen, Yao Liu, et al.Pageof 2