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Expert Opinion on Drug Discovery
|
November 30, 2022
The current progress in the use of boron as a platform for novel antiviral drug design
Shuo Wang, Yujie Ren, Zhao Wang, et al.
Bioorganic Chemistry
|
August 31, 2025
Design, synthesis, and biological evaluation of dual-site HIV-1 inhibitors simultaneously targeting the NNRTI binding pocket and an adjacent site with favorable resistance profiles
Xiangkai Ji, Xiangyi Jiang, Xing Huang, et al.
Journal of Medicinal Chemistry
|
February 17, 2022
Contemporary Medicinal Chemistry Strategies for the Discovery and Development of Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors
Zhao Wang, Srinivasulu Cherukupalli, Minghui Xie, et al.
Medicinal Research Reviews
|
April 20, 2019
Molecular design opportunities presented by solvent-exposed regions of target proteins
Xiangyi Jiang, Ji Yu, Zhongxia Zhou, et al.
European Journal of Medicinal Chemistry
|
March 23, 2020
In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP
Dongwei Kang, Da Feng, Lanlan Jing, et al.
ACS Infectious Diseases
|
July 4, 2020
Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs
Dongwei Kang, Yanying Sun, N Arul Murugan, et al.
Journal of Medicinal Chemistry
|
September 17, 2025
Exploring the HIV-1 Reverse Transcriptase p51/p66 Interface: Structure-Based Design and Optimization of Novel 2,4,6-Trisubstituted Pyrimidines as Potent NNRTIs with Improved Resistance Profiles
Xiangkai Ji, Xiangyi Jiang, Zhen Gao, et al.
Molecules (Basel, Switzerland)
|
September 23, 2022
Design, Synthesis, and Evaluation of a Set of Carboxylic Acid and Phosphate Prodrugs Derived from HBV Capsid Protein Allosteric Modulator NVR 3-778
Xiangkai Ji, Xiangyi Jiang, Chisa Kobayashi, et al.
European Journal of Medicinal Chemistry
|
October 6, 2024
Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant viruses
Xiangyi Jiang, Waleed A Zalloum, Zhen Gao, et al.
European Journal of Medicinal Chemistry
|
December 6, 2020
Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp<sup>3</sup> values and favorable drug-like properties
Xiangyi Jiang, Boshi Huang, Fisayo A Olotu, et al.
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of 5
Search research articles
Search
Showing results (11-20 of 45) with videos related to
Sort By:
Page
of 5
Expert Opinion on Drug Discovery
|
November 30, 2022
The current progress in the use of boron as a platform for novel antiviral drug design
Shuo Wang, Yujie Ren, Zhao Wang, et al.
Bioorganic Chemistry
|
August 31, 2025
Design, synthesis, and biological evaluation of dual-site HIV-1 inhibitors simultaneously targeting the NNRTI binding pocket and an adjacent site with favorable resistance profiles
Xiangkai Ji, Xiangyi Jiang, Xing Huang, et al.
Journal of Medicinal Chemistry
|
February 17, 2022
Contemporary Medicinal Chemistry Strategies for the Discovery and Development of Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors
Zhao Wang, Srinivasulu Cherukupalli, Minghui Xie, et al.
Medicinal Research Reviews
|
April 20, 2019
Molecular design opportunities presented by solvent-exposed regions of target proteins
Xiangyi Jiang, Ji Yu, Zhongxia Zhou, et al.
European Journal of Medicinal Chemistry
|
March 23, 2020
In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP
Dongwei Kang, Da Feng, Lanlan Jing, et al.
ACS Infectious Diseases
|
July 4, 2020
Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs
Dongwei Kang, Yanying Sun, N Arul Murugan, et al.
Journal of Medicinal Chemistry
|
September 17, 2025
Exploring the HIV-1 Reverse Transcriptase p51/p66 Interface: Structure-Based Design and Optimization of Novel 2,4,6-Trisubstituted Pyrimidines as Potent NNRTIs with Improved Resistance Profiles
Xiangkai Ji, Xiangyi Jiang, Zhen Gao, et al.
Molecules (Basel, Switzerland)
|
September 23, 2022
Design, Synthesis, and Evaluation of a Set of Carboxylic Acid and Phosphate Prodrugs Derived from HBV Capsid Protein Allosteric Modulator NVR 3-778
Xiangkai Ji, Xiangyi Jiang, Chisa Kobayashi, et al.
European Journal of Medicinal Chemistry
|
October 6, 2024
Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant viruses
Xiangyi Jiang, Waleed A Zalloum, Zhen Gao, et al.
European Journal of Medicinal Chemistry
|
December 6, 2020
Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp<sup>3</sup> values and favorable drug-like properties
Xiangyi Jiang, Boshi Huang, Fisayo A Olotu, et al.
Page
of 5