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European Journal of Medicinal Chemistry|February 25, 2020
Discovery of novel "Dual-site" binding oseltamivir derivatives as potent influenza virus neuraminidase inhibitorsWei Ai, Jian Zhang, Waleed A Zalloum, et al.RSC Advances|February 25, 2020
Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitorsXiangyi Jiang, Gaochan Wu, Waleed A Zalloum, et al.Molecules (Basel, Switzerland)|September 23, 2022
Design, Synthesis and Structure-Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component ReactionXiangkai Ji, Jing Li, Prem Prakash Sharma, et al.Journal of Medical Virology|April 5, 2024
Discovery of low-molecular-weight phenylalanine derivatives as novel HIV capsid modulators with improved antiretroviral activity and metabolic stabilityXiangyi Jiang, Zhen Gao, Prem Prakash Sharma, et al.Molecules (Basel, Switzerland)|December 11, 2022
Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid ModulatorsShujing Xu, Lin Sun, Waleed A Zalloum, et al.RSC Medicinal Chemistry|July 24, 2023
Design, synthesis, and mechanistic study of 2-piperazineone-bearing peptidomimetics as novel HIV capsid modulatorsXujie Zhang, Lin Sun, Shujing Xu, et al.Journal of Medicinal Chemistry|October 17, 2024
"Pseudosubstrate Envelope"/Free Energy Perturbation-Guided Design and Mechanistic Investigations of Benzothiazole HIV Capsid Modulators with High Ligand EfficiencyShujing Xu, Shuo Wang, Yang Zhou, et al.Journal of Medicinal Chemistry|February 6, 2019
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety ProfilesBoshi Huang, Wenmin Chen, Tong Zhao, et al.Journal of Medical Virology|August 10, 2022
Discovery of novel 1,2,4-triazole phenylalanine derivatives targeting an unexplored region within the interprotomer pocket of the HIV capsid proteinXiangyi Jiang, Prem Prakash Sharma, Brijesh Rathi, et al.European Journal of Medicinal Chemistry|September 30, 2021
Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitorsXujie Zhang, Lin Sun, Megan E Meuser, et al.Pageof 5