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Bioorganic & Medicinal Chemistry Letters|December 21, 2011
Facile synthesis of tetracyclic azepine and oxazocine derivatives and their potential as MAPKAP-K2 (MK2) inhibitorsAshwin U Rao, Dong Xiao, Xianhai Huang, et al.Bioorganic & Medicinal Chemistry Letters|December 16, 2011
A three-step protocol for lead optimization: quick identification of key conformational features and functional groups in the SAR studies of non-ATP competitive MK2 (MAPKAPK2) inhibitorsXianhai Huang, Xiaohong Zhu, Xiao Chen, et al.Journal of the American Chemical Society|August 12, 2004
Studies toward diazonamide A: development of a hetero-pinacol macrocyclization cascade for the construction of the bis-macrocyclic framework of the originally proposed structureK C Nicolaou, Scott A Snyder, Nicolas Giuseppone, et al.ACS Medicinal Chemistry Letters|June 6, 2014
The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase ModulatorsXianhai Huang, Robert Aslanian, Wei Zhou, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Potent Pyrazolopyridine Series of γ-Secretase ModulatorsJun Qin, Wei Zhou, Xianhai Huang, et al.ACS Medicinal Chemistry Letters|October 24, 2017
Discovery of a Tetrahydrobenzisoxazole Series of γ-Secretase ModulatorsZhiqiang Zhao, Dmitri A Pissarnitski, Xianhai Huang, et al.Bioorganic & Medicinal Chemistry Letters|November 8, 2017
The synthesis of 2,3,6-trisubstituted 1-oxo-1,2-dihydroisoquinolines as potent CRTh<sub>2</sub> antagonistsXianhai Huang, Ashwin Rao, Wei Zhou, et al.Bioorganic & Medicinal Chemistry Letters|April 23, 2013
Conformation constraint of anilides enabling the discovery of tricyclic lactams as potent MK2 non-ATP competitive inhibitorsDong Xiao, Anandan Palani, Xianhai Huang, et al.Journal of the American Chemical Society|October 8, 2004
Chemistry and biology of diazonamide A: second total synthesis and biological investigationsK C Nicolaou, Junliang Hao, Mali V Reddy, et al.Journal of Medicinal Chemistry|August 14, 2020
Generation of Leads for γ-Secretase ModulationMihirbaran Mandal, Alexei Buevich, John P Caldwell, et al.Pageof 4