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Nature|February 1, 2023
Reducing affinity as a strategy to boost immunomodulatory antibody agonismXiaojie Yu, Christian M Orr, H T Claude Chan, et al.Cellular and Molecular Gastroenterology and Hepatology|February 27, 2022
Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular SecretionXiaojie Yu, Natalia Elfimova, Marion Müller, et al.The Journal of Clinical Investigation|April 9, 2013
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activityMargaret E Ackerman, Max Crispin, Xiaojie Yu, et al.Mabs|February 25, 2016
A bispecific antibody effectively neutralizes all four serotypes of dengue virus by simultaneous blocking virus attachment and fusionXin Shi, Yongqiang Deng, Huajing Wang, et al.Oncotarget|September 9, 2017
The anti-ErbB2 antibody H2-18 and the pan-PI3K inhibitor GDC-0941 effectively inhibit trastuzumab-resistant ErbB2-overexpressing breast cancerLingfei Wang, Xiaojie Yu, Chao Wang, et al.Cancer Cell|May 23, 2020
Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor ActivityXiaojie Yu, H T Claude Chan, Hayden Fisher, et al.International Journal of Medical Microbiology : IJMM|August 17, 2016
Genetic features of livestock-associated Staphylococcus aureus ST9 isolates from Chinese pigs that carry the lsa(E) gene for quinupristin/dalfopristin resistanceXiaomei Yan, Zongwei Li, Monika A Chlebowicz, et al.Communications Biology|June 24, 2021
TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activityXiaojie Yu, Sonya James, James H Felce, et al.Science Immunology|July 20, 2022
Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibilityChristian M Orr, Hayden Fisher, Xiaojie Yu, et al.Cancer Cell|March 27, 2018
Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 AntibodiesXiaojie Yu, H T Claude Chan, Christian M Orr, et al.Pageof 15