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Bioorganic & Medicinal Chemistry Letters|February 11, 2015
Synthesis and SAR study of potent and selective PI3Kδ inhibitorsMinna Bui, Xiaolin Hao, Youngsook Shin, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Potent and Orally Bioavailable GPR142 Agonists as Novel Insulin Secretagogues for the Treatment of Type 2 DiabetesNarihiro Toda, Xiaolin Hao, Yasuyuki Ogawa, et al.Journal of Medicinal Chemistry|August 11, 2012
Discovery and in vivo evaluation of dual PI3Kβ/δ inhibitorsFelix Gonzalez-Lopez de Turiso, Youngsook Shin, Matthew Brown, et al.Journal of Medicinal Chemistry|March 28, 2014
Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodentsBrian M Fox, Kazuyuki Sugimoto, Kiyosei Iio, et al.Journal of Medicinal Chemistry|July 15, 2016
Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-1430)Felix Gonzalez-Lopez de Turiso, Xiaolin Hao, Youngsook Shin, et al.Bioorganic & Medicinal Chemistry Letters|November 16, 2010
A novel series of IKKβ inhibitors part II: description of a potent and pharmacologically active series of analogsTimothy D Cushing, Vijay Baichwal, Karen Berry, et al.Bioorganic & Medicinal Chemistry Letters|November 16, 2010
A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hitTimothy D Cushing, Vijay Baichwal, Karen Berry, et al.Journal of Medicinal Chemistry|December 4, 2014
Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune diseaseTimothy D Cushing, Xiaolin Hao, Youngsook Shin, et al.Pageof 2