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Briefings in Bioinformatics|August 22, 2023
TransFoxMol: predicting molecular property with focused attentionJian Gao, Zheyuan Shen, Yufeng Xie, et al.European Journal of Medicinal Chemistry|May 8, 2024
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expressionYang Lu, Jian Gao, Peipei Wang, et al.JACS Au|January 30, 2026
PSMA-Targeting Chimeras for Cell-Type-Specific Degradation of Surface Immune Checkpoint Protein PD-L1Yuqing Luo, Xiaoxiao Gong, Keren Peng, et al.European Journal of Medicinal Chemistry|November 27, 2024
Discovery of a potent PARP1 PROTAC as a chemosensitizer for the treatment of colorectal cancerMingfei Wu, Yiming Jiang, Daoming Zhang, et al.Journal of Medicinal Chemistry|July 12, 2024
Discovery of New Phenyltetrazolium Derivatives as Ferroptosis Inhibitors for Treating Ischemic Stroke: An Example Development from Free Radical ScavengersYang Lu, Zexu Shen, Yaping Xu, et al.Journal of Medicinal Chemistry|August 10, 2021
Discovery of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous ToxicityJinxin Che, Xiaoyang Dai, Jian Gao, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|January 25, 2024
Rational Identification of Novel Antibody-Drug Conjugate with High Bystander Killing Effect against Heterogeneous TumorsYu Guo, Zheyuan Shen, Wenbin Zhao, et al.Journal of Medicinal Chemistry|July 31, 2024
Discovery of an Exceptionally Orally Bioavailable and Potent HPK1 PROTAC with Enhancement of Antitumor Efficacy of Anti-PD-L1 TherapyMingfei Wu, Yiquan Wu, Yuyuan Jin, et al.Journal of Medicinal Chemistry|January 17, 2024
Discovery of N-(1-(6-Oxo-1,6-dihydropyrimidine)-pyrazole) Acetamide Derivatives as Novel Noncovalent DprE1 Inhibitors against Mycobacterium tuberculosisLiu Yang, Xueping Hu, Yang Lu, et al.Journal of Medicinal Chemistry|June 7, 2022
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of LymphomaJingyu Zhang, Jinxin Che, Xiaomin Luo, et al.Pageof 19