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Journal of Medicinal Chemistry|July 13, 2019
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based DesignXiaowu Dong, Wenhu Zhan, Mengting Zhao, et al.
European Journal of Medicinal Chemistry|November 4, 2024
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemiaJingyu Zhang, Haiting Duan, Renzhao Gui, et al.
Nucleic Acids Research|October 13, 2023
ADCdb: the database of antibody-drug conjugatesLiteng Shen, Xiuna Sun, Zhen Chen, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|June 29, 2026
Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress-Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric CancerQianqian Xu, Guangzhao Pan, Lele Zhang, et al.
Bioorganic Chemistry|January 24, 2025
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptidesGongruixue Zeng, Gaoya Xu, Lixin Gao, et al.
Bioorganic & Medicinal Chemistry|November 5, 2024
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protectionQian Yu, Lixin Gao, Linhao Xu, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|August 27, 2025
Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ DamageGuotao Lu, Fei Han, Yaodong Wang, et al.
British Journal of Pharmacology|April 19, 2021
Acinar cell NLRP3 inflammasome and gasdermin D (GSDMD) activation mediates pyroptosis and systemic inflammation in acute pancreatitisLin Gao, Xiaowu Dong, Weijuan Gong, et al.
Nucleic Acids Research|October 3, 2024
PDCdb: the biological activity and pharmaceutical information of peptide-drug conjugate (PDC)Xiuna Sun, Hanyang Li, Zhen Chen, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|July 25, 2024
PROTAC-Mediated HDAC7 Protein Degradation Unveils Its Deacetylase-Independent Proinflammatory Function in MacrophagesKailibinuer Kadier, Tian Niu, Baoli Ding, et al.
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