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Journal of Medicinal Chemistry
|
March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors
Michael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry
|
April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
Brian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry
|
August 18, 2017
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates
Antonia F Stepan, Michelle M Claffey, Matthew R Reese, et al.
Page
of 5
Search research articles
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Showing results (41-50 of 43) with videos related to
Sort By:
Page
of 5
You have reached the last page of results.
This site can display upto 43 results.
Journal of Medicinal Chemistry
|
March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors
Michael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry
|
April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
Brian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry
|
August 18, 2017
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates
Antonia F Stepan, Michelle M Claffey, Matthew R Reese, et al.
Page
of 5