Showing results (1-10 of 9) with videos related to
Sort By:
Pageof 1
Biopolymers|February 3, 2004
Calculation of ligand-nucleic acid binding free energies with the generalized-born model in DOCKXinshan Kang, Richard H Shafer, Irwin D KuntzJournal of Medicinal Chemistry|April 2, 2005
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SAJunmei Wang, Xinshan Kang, Irwin D Kuntz, et al.Bioorganic & Medicinal Chemistry Letters|September 11, 2012
Synthesis and biological evaluation of crown ether fused quinazoline analogues as potent EGFR inhibitorsShaojing Hu, Guojian Xie, Don X Zhang, et al.Journal of Medicinal Chemistry|August 10, 2007
Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarctionMoorthy S S Palanki, Elena Dneprovskaia, John Doukas, et al.Bioorganic & Medicinal Chemistry Letters|September 11, 2007
The design and preliminary structure-activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymesJianguo Cao, Richard Fine, Colleen Gritzen, et al.Current Topics in Medicinal Chemistry|August 5, 2008
Inhibitors of ABL and the ABL-T315I mutationGlenn Noronha, Jianguo Cao, Chun P Chow, et al.Bioorganic & Medicinal Chemistry Letters|August 26, 2006
Discovery and preliminary structure-activity relationship studies of novel benzotriazine based compounds as Src inhibitorsGlenn Noronha, Kathy Barrett, Jianguo Cao, et al.Journal of Medicinal Chemistry|March 4, 2008
Development of prodrug 4-chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl benzoate (TG100801): a topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degenerationMoorthy S S Palanki, Hideo Akiyama, Peter Campochiaro, et al.Bioorganic & Medicinal Chemistry Letters|November 23, 2006
Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine--a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assaysGlenn Noronha, Kathy Barrett, Antonio Boccia, et al.Pageof 1