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Journal of Medical Virology|July 29, 2024
Structure-based design, synthesis, and biological characterization of indolylarylsulfone derivatives as novel human immunodeficiency virus type 1 inhibitors with potent antiviral activities and favorable drug-like profilesZhao Wang, Wenbo Wang, Zhen Gao, et al.European Journal of Medicinal Chemistry|August 26, 2021
Design, synthesis and evaluation of heteroaryldihydropyrimidine analogues bearing spiro ring as hepatitis B virus capsid protein inhibitorsYue Ma, Shujie Zhao, Yujie Ren, et al.European Journal of Medicinal Chemistry|July 24, 2025
Further exploring the tolerant region II: Identification of 2,4,5-trisubstituted pyrimidines as HIV-1 reverse transcriptase allosteric inhibitors with desirable antiviral activities and reduced cytotoxicityZhenzhen Zhou, Lin Zheng, Wenbo Jiang, et al.Signal Transduction and Targeted Therapy|December 29, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signalingYi Zheng, Meng-Wei Zhuang, Lulu Han, et al.European Journal of Medicinal Chemistry|August 2, 2024
Discovery of 2,4,6-trisubstituted pyrimidine derivatives as novel potent HIV-1 NNRTIs by exploiting the tolerant region II of the NNIBPZhenzhen Zhou, Yanying Sun, Yanyang Qin, et al.Bioorganic Chemistry|August 31, 2025
Design, synthesis, and biological evaluation of dual-site HIV-1 inhibitors simultaneously targeting the NNRTI binding pocket and an adjacent site with favorable resistance profilesXiangkai Ji, Xiangyi Jiang, Xing Huang, et al.Journal of Medicinal Chemistry|February 28, 2024
Structure-Based Design of Novel G-Protein-Coupled Receptor TAAR1 Agonists as Potential Antipsychotic Drug CandidatesZhenzhen Zhou, Weifeng Zhang, Fabao Zhao, et al.Journal of Medical Virology|March 7, 2024
Structure-based design of diarylpyrimidines and triarylpyrimidines as potent HIV-1 NNRTIs with improved metabolic stability and drug resistance profilesMinghui Xie, Zhao Wang, Fabao Zhao, et al.Acta Pharmaceutica Sinica. B|July 19, 2024
Design and optimization of piperidine-substituted thiophene[3,2-d]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profilesYanying Sun, Zhenzhen Zhou, Zhongling Shi, et al.European Journal of Medicinal Chemistry|December 28, 2022
Identification of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptaseDa Feng, Xiaofang Zuo, Fabao Zhao, et al.Pageof 40