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European Journal of Medicinal Chemistry|August 21, 2024
Discovery of potent HIV-1 NNRTIs by CuAAC click-chemistry-based miniaturized synthesis, rapid screening and structure optimizationLanlan Jing, Gaochan Wu, Fabao Zhao, et al.European Journal of Medicinal Chemistry|October 7, 2023
Development of chalcone-like derivatives and their biological and mechanistic investigations as novel influenza nuclear export inhibitorsChuanfeng Liu, Ying Zhang, Ping Li, et al.Signal Transduction and Targeted Therapy|January 25, 2022
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granulesYi Zheng, Jian Deng, Lulu Han, et al.Acta Pharmaceutica Sinica. B|June 13, 2020
Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIsDongwei Kang, Da Feng, Tiziana Ginex, et al.European Journal of Medicinal Chemistry|November 29, 2022
Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs: Crystallographic overlay-based molecular design, synthesis, and biological evaluationDa Feng, Hao Lin, Liyang Jiang, et al.Archives of Pharmacal Research|August 9, 2012
Arylazolyl(azinyl)thioacetanilide. Part 9: Synthesis and biological investigation of thiazolylthioacetamides derivatives as a novel class of potential antiviral agentsPeng Zhan, Liu Wang, Hong Liu, et al.European Journal of Medicinal Chemistry|May 31, 2022
Chemical space exploration around indolylarylsulfone scaffold led to a novel class of highly active HIV-1 NNRTIs with spiro structural featuresShenghua Gao, Yusen Cheng, Shu Song, et al.Journal of Medicinal Chemistry|January 21, 2022
Development of Novel Dihydrofuro[3,4-d]pyrimidine Derivatives as HIV-1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181CDongwei Kang, Yanying Sun, Da Feng, et al.European Journal of Medicinal Chemistry|January 28, 2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approachesBoshi Huang, Cuicui Li, Wenmin Chen, et al.International Journal of Molecular Sciences|August 29, 2024
Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological EvaluationZongji Zhuo, Zhao Wang, Lanlan Jing, et al.Pageof 40