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Bioorganic & Medicinal Chemistry|September 25, 2021
Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitorsJing Li, Xiangyi Jiang, Alexej Dick, et al.Journal of Medicinal Chemistry|August 20, 2016
Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance ProfilesDongwei Kang, Zengjun Fang, Zhenyu Li, et al.European Journal of Medicinal Chemistry|August 17, 2021
Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitorsDongwei Kang, Çagil Urhan, Fenju Wei, et al.European Journal of Medicinal Chemistry|July 2, 2023
Discovery of novel diarypyrimidine derivatives bearing six-membered non-aromatic heterocycles as potent HIV-1 NNRTIs with improved anti-resistance and drug-like profilesXiangyi Jiang, Boshi Huang, Waleed A Zalloum, et al.Chemical Biology & Drug Design|November 2, 2018
Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions IDongwei Kang, Zhao Wang, Meng Chen, et al.Journal of Medicinal Chemistry|January 15, 2020
Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion ChannelDongwei Kang, F Xavier Ruiz, Da Feng, et al.Journal of Medicinal Chemistry|July 13, 2026
Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug ResistanceMei Wang, Zeyu Peng, Yang Zhou, et al.Journal of Medicinal Chemistry|January 26, 2023
Structure-Based Optimization of 2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Exploiting the Tolerant Regions of the Non-Nucleoside Reverse Transcriptase Inhibitors' Binding PocketFabao Zhao, Heng Zhang, Minghui Xie, et al.Bioorganic Chemistry|September 18, 2021
Design, synthesis, and antiviral evaluation of novel piperidine-substituted arylpyrimidines as HIV-1 NNRTIs by exploring the hydrophobic channel of NNIBPTao Zhang, Zhongxia Zhou, Waleed A Zalloum, et al.European Journal of Medicinal Chemistry|March 17, 2023
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like propertiesRuifang Jia, Jiwei Zhang, Fangyuan Shi, et al.Pageof 40