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Proceedings of the National Academy of Sciences of the United States of America|June 2, 2019
LSD1 destabilizes FBXW7 and abrogates FBXW7 functions independent of its demethylase activityHuiyin Lan, Mingjia Tan, Qiang Zhang, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 28, 2010
Validation of SAG/RBX2/ROC2 E3 ubiquitin ligase as an anticancer and radiosensitizing targetLijun Jia, Jie Yang, Xinbao Hao, et al.
Molecular Oncology|November 15, 2018
SCFβ-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivationYing Ma, Danrui Cui, Xiufang Xiong, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 25, 2019
The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cellsYuan Yin, Chuan-Ming Xie, Hua Li, et al.
Frontiers in Immunology|December 22, 2018
SAG/RBX2 E3 Ubiquitin Ligase Differentially Regulates Inflammatory Responses of Myeloid Cell SubsetsXiufang Xiong, Nathan D Mathewson, Hua Li, et al.
The Journal of Biological Chemistry|August 10, 2025
Neddylation inhibitor MLN4924 enhances H3K18 lactylation via binding to LDH and downregulates ITGB4 to block metastasisHongfei Yu, Qiyin Zhou, Yongxia Chen, et al.
Cell Death and Differentiation|April 1, 2025
DEPTOR suppresses lymphomagenesis by promoting EGFR degradation via HUWE1 E3 ligaseXiufang Xiong, Xiaoyu Chen, Shengpeng Shao, et al.
Acta Pharmaceutica Sinica. B|December 13, 2021
Discovery of a small molecule inhibitor of cullin neddylation that triggers ER stress to induce autophagyYanan Li, Chaorong Wang, Tiantian Xu, et al.
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