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Cancer Science|October 20, 2021
P90 ribosomal S6 kinase confers cancer cell survival by mediating checkpoint kinase 1 degradation in response to glucose stressYing Ma, Danrui Cui, Linchen Wang, et al.Cell Death & Disease|October 3, 2022
PD-L1 induction via the MEK-JNK-AP1 axis by a neddylation inhibitor promotes cancer-associated immunosuppressionShizhen Zhang, Xiahong You, Tiantian Xu, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|October 29, 2025
The Crosstalk Between CRL5 and APC/C E3 Ligases Regulates Metastasis and Chemosensitivity of Cancer CellsDanrui Cui, Ruirui Qu, Tianqi Li, et al.Cell Reports|March 14, 2019
The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling PathwaysChuan-Ming Xie, Mingjia Tan, Xiao-Tong Lin, et al.Nature Communications|January 17, 2017
The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressorJie Xu, Weihua Zhou, Fei Yang, et al.Science Bulletin|November 4, 2025
LD-110, a potent LSD1 PROTAC degrader, suppresses tumor growth by inducing ER stress and apoptosisDanyi Zhai, Jiezhen Zhuo, Yudong Yin, et al.Journal of Medicinal Chemistry|October 6, 2025
Discovery of LD-110 as an Effective LSD1 PROTAC Degrader for the Treatment of Esophagus Squamous CancerJiezhen Zhuo, Danyi Zhai, Lihua Liu, et al.Signal Transduction and Targeted Therapy|October 17, 2022
A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancerTiantian Xu, Qisheng Ma, Yanan Li, et al.Oncogene|November 6, 2019
DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signalsXiaoyu Chen, Xiufang Xiong, Danrui Cui, et al.Cancer Letters|September 1, 2025
UBE2C promotes pancreatic tumorigenesis by KRAS stabilization via APC/CCDH1-mediated WDR76 degradationLinchen Wang, Xiaoyu Chen, Ruirui Qu, et al.Pageof 6