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Advanced Materials (Deerfield Beach, Fla.)|January 28, 2026
High-Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ ImmunoengineeringAlex G Hamilton, Ajay S Thatte, Junchao Xu, et al.Nature Nanotechnology|March 19, 2026
Prodrug-tethered lipid nanoparticles for synergistic messenger RNA cancer immunotherapyQiangqiang Shi, Ningqiang Gong, Jinjin Wang, et al.Nature Communications|January 24, 2025
Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineeringMarshall S Padilla, Kaitlin Mrksich, Yiming Wang, et al.Science Translational Medicine|January 31, 2024
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissueGan Zhao, Lulu Xue, Aaron I Weiner, et al.Cell Reports|October 8, 2023
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunityWenqun Zhong, Youtao Lu, Xuexiang Han, et al.Journal of Controlled Release : Official Journal of the Controlled Release Society|December 26, 2021
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)Hamideh Parhiz, Jacob S Brenner, Priyal N Patel, et al.Nature Nanotechnology|October 1, 2024
Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic deliveryLulu Xue, Gan Zhao, Ningqiang Gong, et al.Nature Nanotechnology|June 23, 2025
Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modificationsMáté Vadovics, Wenchen Zhao, Emily F Daley, et al.Pageof 7