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European Journal of Medicinal Chemistry|January 31, 2024
Discovery of a novel, highly potent EZH2 PROTAC degrader for targeting non-canonical oncogenic functions of EZH2Julia Velez, Brandon Dale, Kwang-Su Park, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2016
Synthesis and antibacterial evaluation of macrocyclic diarylheptanoid derivativesHao Lin, David F Bruhn, Marcus M Maddox, et al.
Journal of Medicinal Chemistry|June 8, 2022
Exploring Degradation of Mutant and Wild-Type Epidermal Growth Factor Receptors Induced by Proteolysis-Targeting ChimerasXufen Yu, Meng Cheng, Kaylene Lu, et al.
Stem Cell Research|June 5, 2021
Inhibition of EZH2 primes the cardiac gene activation via removal of epigenetic repression during human direct cardiac reprogrammingYawen Tang, Lianzhong Zhao, Xufen Yu, et al.
Cell Chemical Biology|June 24, 2023
Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimizationMartin P Schwalm, Andreas Krämer, Anja Dölle, et al.
Journal of the American Chemical Society|July 5, 2022
TF-DUBTACs Stabilize Tumor Suppressor Transcription FactorsJing Liu, Xufen Yu, He Chen, et al.
Human Gene Therapy|August 25, 2023
Chemical Epigenetic Regulation of Adeno-Associated Virus Delivered TransgenesJessica D Umaña, Sara R Wasserman, Liujiang Song, et al.
International Journal of Molecular Sciences|April 17, 2025
Novel Compounds Target Aberrant Calcium Signaling in the Treatment of Relapsed High-Risk NeuroblastomaDana-Lynn T Koomoa, Nathan Sunada, Italo Espinoza-Fuenzalida, et al.
Bioorganic & Medicinal Chemistry|October 8, 2011
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agentsLi Shen, Eun-Jung Park, Tamara P Kondratyuk, et al.
Science Advances|April 23, 2025
Pharmacologic degradation of WDR5 suppresses oncogenic activities of SS18::SSX and provides a therapeutic of synovial sarcomaYao Yu, Xufen Yu, Bo Pan, et al.
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