Showing results (41-50 of 100) with videos related to
Sort By:
Pageof 10
Nucleic Acids Research|October 27, 2022
A cryptic transactivation domain of EZH2 binds AR and AR's splice variant, promoting oncogene activation and tumorous transformationJun Wang, Kwang-Su Park, Xufen Yu, et al.European Journal of Medicinal Chemistry|April 29, 2023
Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategySong Chen, Zhendong Chen, Lixue Lu, et al.Bioorganic & Medicinal Chemistry Letters|October 27, 2007
Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea libraryDianqing Sun, Victoria Jones, Elizabeth I Carson, et al.ACS Infectious Diseases|April 10, 2024
Evaluation of <i>Fusobacterium nucleatum</i> Enoyl-ACP Reductase (FabK) as a Narrow-Spectrum Drug TargetJacob T Rutherford, Kristiana Avad, Chetna Dureja, et al.Journal of Medicinal Chemistry|July 13, 2019
Design, Synthesis, and Characterization of Ogerin-Based Positive Allosteric Modulators for G Protein-Coupled Receptor 68 (GPR68)Xufen Yu, Xi-Ping Huang, Terry P Kenakin, et al.Journal of Medicinal Chemistry|June 25, 2015
Structure-based design of potent HIV-1 protease inhibitors with modified P1-biphenyl ligands: synthesis, biological evaluation, and enzyme-inhibitor X-ray structural studiesArun K Ghosh, Xufen Yu, Heather L Osswald, et al.Journal of Medicinal Chemistry|October 5, 2022
Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant CellsXufen Yu, Jia Xu, Kaitlyn M Cahuzac, et al.European Journal of Medicinal Chemistry|March 4, 2025
Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic propertiesYing Lin, Jing Liu, Xinjian Tian, et al.Antimicrobial Agents and Chemotherapy|January 24, 2024
<i>In vivo</i> evaluation of <i>Clostridioides difficile</i> enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategyChetna Dureja, Jacob T Rutherford, Fahad B A Pavel, et al.Biorxiv : the Preprint Server for Biology|October 4, 2023
<i>In vivo</i> evaluation of <i>Clostridioides difficile</i> enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategyChetna Dureja, Jacob T Rutherford, Fahad B A Pavel, et al.Pageof 10