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ACS Bio & Med Chem Au|February 23, 2026
Structural and Biochemical Characterization of <i>Fusobacterium nucleatum</i> Enoyl-ACP Reductase II (FabK) Reveals the Basis for Bacterial Species-Specific InhibitionKristiana Avad, Osama Alaidi, Destiny Okpomo, et al.
Bioorganic & Medicinal Chemistry Letters|October 17, 2007
Discovery of novel isoxazolines as anti-tuberculosis agentsRajendra P Tangallapally, Dianqing Sun, Rakesh, et al.
ACS Chemical Biology|June 12, 2019
Small-Molecule Inhibition of the <i>C. difficile</i> FAS-II Enzyme, FabK, Results in Selective ActivityJesse A Jones, Allan M Prior, Ravi K R Marreddy, et al.
ACS Infectious Diseases|December 4, 2018
The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile InfectionRavi K R Marreddy, Xiaoqian Wu, Madhab Sapkota, et al.
Journal of Medicinal Chemistry|February 4, 2022
Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure-Activity Relationship StudiesXufen Yu, Jia Xu, Yudao Shen, et al.
Bioorganic & Medicinal Chemistry|May 24, 2023
Synthesis and evaluation of phenylimidazole FabK inhibitors as new Anti-C. Difficile agentsKrissada Norseeda, Fahad Bin Aziz Pavel, Jacob T Rutherford, et al.
Journal of Medicinal Chemistry|January 3, 2020
Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-Molecule DegradersMeng Cheng, Xufen Yu, Kaylene Lu, et al.
Journal of Medicinal Chemistry|December 2, 2021
Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase DegradersXufen Yu, Jia Xu, Ling Xie, et al.
Journal of Medicinal Chemistry|May 13, 2026
Targeted Degradation of Prolyl Hydroxylase Domain Enzyme 1 (PHD1) as a Novel Therapeutic Strategy for Acetaminophen-Induced Acute Liver InjuryHuahua Su, Yuting Li, Ting Xie, et al.
The Journal of Antibiotics|April 4, 2013
Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agentsLi Shen, Marcus M Maddox, Sudip Adhikari, et al.
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