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Oncogene|February 6, 2023
Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degraderXufen Yu, Jun Wang, Weida Gong, et al.ACS Pharmacology & Translational Science|July 15, 2022
Targeting Triple-Negative Breast Cancer by a Novel Proteolysis Targeting Chimera Degrader of Enhancer of Zeste Homolog 2Brandon Dale, Chris Anderson, Kwang-Su Park, et al.Nature Biotechnology|November 13, 2019
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machineryAnna M Chiarella, Kyle V Butler, Berkley E Gryder, et al.Journal of Medicinal Chemistry|August 14, 2020
Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) DegradersYudao Shen, Guozhen Gao, Xufen Yu, et al.ACS Chemical Neuroscience|August 8, 2019
Designing Functionally Selective Noncatechol Dopamine D<sub>1</sub> Receptor Agonists with Potent In Vivo Antiparkinsonian ActivityMichael L Martini, Caroline Ray, Xufen Yu, et al.Bioorganic & Medicinal Chemistry Letters|September 8, 2015
Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosumUi Joung Youn, Tawanun Sripisut, Eun-Jung Park, et al.ACS Combinatorial Science|February 13, 2018
Solid-Phase Synthesis and Antibacterial Activity of Cyclohexapeptide Wollamide B AnalogsLissa S Tsutsumi, John M Elmore, Uyen T Dang, et al.Bioorganic & Medicinal Chemistry|December 9, 2009
Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC)Sharmila Sivendran, Victoria Jones, Dianqing Sun, et al.Journal of Natural Products|February 19, 2014
Herbicidin congeners, undecose nucleosides from an organic extract of Streptomyces sp. L-9-10Xingyun Chai, Ui Joung Youn, Dianqing Sun, et al.Journal of Medicinal Chemistry|July 8, 2026
RIMTAC: A Novel Degrader Design Platform by Indirect VHL-Recruitment via RIPK1Chang Shen, Hanyin Sun, Ruining Li, et al.Pageof 10