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Journal of Medicinal Chemistry|July 8, 2026
RIMTAC: A Novel Degrader Design Platform by Indirect VHL-Recruitment via RIPK1Chang Shen, Hanyin Sun, Ruining Li, et al.Nature Communications|April 17, 2026
ELMO2 is a therapeutic vulnerability in mesenchymal-like and drug-resistant non-small cell lung cancerMin Li, Ying Xue, Yuhan Chang, et al.Journal of Medicinal Chemistry|March 16, 2019
Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D<sub>1</sub> Receptor AgonistsMichael L Martini, Jing Liu, Caroline Ray, et al.Proceedings of the National Academy of Sciences of the United States of America|February 26, 2022
A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemiaZhihong Ren, Arum Kim, Yu-Ting Huang, et al.Developmental Cell|September 2, 2021
UV-induced reduction in Polycomb repression promotes epidermal pigmentationMeng-Yen Li, Pooja Flora, Hong Pu, et al.Science Advances|December 5, 2025
Tumor microenvironment-targeted PROTAC nanoparticle self-assembly broadly predicted by structural descriptorsKristen C Vogt, Magdalini Panagiotakopoulou, Mandana T Manzari Honu, et al.Journal of the American Chemical Society|April 10, 2024
USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPKJing Liu, Xiaoping Hu, Kaixiu Luo, et al.Journal of Medicinal Chemistry|November 29, 2023
Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic CancerXufen Yu, Dongxu Li, Jithesh Kottur, et al.Journal of Medicinal Chemistry|June 17, 2026
Unique Cysteine-Directed Covalent Inhibition of PRMT1 Suppresses Breast TumorigenesisMin Shao, Ruining Li, Jinglei Hu, et al.Biorxiv : the Preprint Server for Biology|March 18, 2024
Targeting G9a translational mechanism of SARS-CoV-2 pathogenesis for multifaceted therapeutics of COVID-19 and its sequalaeAdil Muneer, Ling Xie, Xuping Xie, et al.Pageof 6