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Journal of Medicinal Chemistry|January 6, 2026
Design, Synthesis, and Biological Evaluation of the First Novel Macrocycle-Based FGFR Inhibitors That Overcome Clinically Acquired ResistanceShuang Xiang, Xiaojuan Chen, Jieying Lin, et al.Cancer Letters|November 5, 2021
Sirtuin 7 super-enhancer drives epigenomic reprogramming in hepatocarcinogenesisFeng Wu, Liangliang Xu, Yalin Tu, et al.Cancer Letters|September 18, 2022
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in gliomaTian Liu, Yubing Wang, Yiwei Wang, et al.Cancer Research|July 14, 2025
FADD Activation in Hepatocellular Carcinoma Potentiates CD8+T Cell Responses and Sensitizes to Immune Checkpoint InhibitorsJiahuan Lu, Thomas Ting-Hei Chan, Yun Wang, et al.Science Translational Medicine|April 8, 2021
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinomaWeiqin Yang, Yu Feng, Jingying Zhou, et al.Gut|November 1, 2024
Pharmacological activation of STAT1-GSDME pyroptotic circuitry reinforces epigenetic immunotherapy for hepatocellular carcinomaYalin Tu, Haoran Wu, Chengpeng Zhong, et al.Gut|April 5, 2023
Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinomaZhewen Xiong, Stephen Lam Chan, Jingying Zhou, et al.Cancer Cell|June 8, 2026
Tumor cells metabolically resist immune-checkpoint therapy by macrophage efferocytosis-mediated fatty acid recyclingZhixian Liang, Xiaohang Long, Zhewen Xiong, et al.Pageof 2