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Journal of Medicinal Chemistry|August 21, 2007
Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding siteDouglas P Wilson, Zhao-Kui Wan, Wei-Xin Xu, et al.
ACS Chemical Biology|August 5, 2014
An unbiased approach to identify endogenous substrates of "histone" deacetylase 8David E Olson, Namrata D Udeshi, Noah A Wolfson, et al.
ACS Chemical Biology|December 8, 2015
An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell ProtectionFlorence F Wagner, Morten Lundh, Taner Kaya, et al.
Nature Biotechnology|March 2, 2016
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell linesChanning Yu, Aristotle M Mannan, Griselda Metta Yvone, et al.
Journal of the American Chemical Society|November 12, 2010
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitorsLisa A Marcaurelle, Eamon Comer, Sivaraman Dandapani, et al.
ACS Chemical Biology|February 28, 2018
Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic TreatmentMichel Weïwer, Qihong Xu, Jennifer P Gale, et al.
Science Translational Medicine|March 9, 2018
Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemiaFlorence F Wagner, Lina Benajiba, Arthur J Campbell, et al.
ACS Chemical Biology|April 30, 2016
Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional EffectsFlorence F Wagner, Joshua A Bishop, Jennifer P Gale, et al.
Nature Genetics|November 1, 2011
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2Wei-Hua Yue, Hai-Feng Wang, Liang-Dan Sun, et al.
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