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Cancer Discovery|November 28, 2019
Resistance Mechanisms to SYK Inhibition in Acute Myeloid LeukemiaAnjali Cremer, Jana M Ellegast, Gabriela Alexe, et al.Science Translational Medicine|January 3, 2024
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AMLEmily C Wheeler, Benjamin J E Martin, William C Doyle, et al.The Journal of Clinical Investigation|March 17, 2009
The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse modelThomas Mercher, Glen D Raffel, Sandra A Moore, et al.Blood|October 27, 2025
Multiselective RAS(ON) inhibition targets oncogenic RAS and overcomes RAS-mediated resistance to FLT3i and BCL2i in AMLBogdan Popescu, Matthew F Jones, Madison Piao, et al.Cancer Discovery|April 11, 2022
Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML BlastsJana M Ellegast, Gabriela Alexe, Amanda Hamze, et al.Nature Medicine|February 14, 2017
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemiaNina Fenouille, Christopher F Bassil, Issam Ben-Sahra, et al.The Journal of Experimental Medicine|June 22, 2016
Targeting MTHFD2 in acute myeloid leukemiaYana Pikman, Alexandre Puissant, Gabriela Alexe, et al.The Journal of Molecular Diagnostics : JMD|July 7, 2023
Outlier Expression of Isoforms by Targeted or Total RNA Sequencing Identifies Clinically Significant Genomic Variants in Hematolymphoid TumorsHarrison K Tsai, Tasos Gogakos, Va Lip, et al.Nature Communications|November 21, 2025
Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemiaCaroline R M Wiggers, Eugene Y Cho, Merve Ozdemir, et al.Blood Advances|May 5, 2026
Combining Menin and MEK inhibition to target poor prognosis KMT2A-rearranged RAS pathway-mutant acute myeloid leukemiaNastassja Keora Scheidegger, Constanze Schneider, Gabriela Alexe, et al.Pageof 6