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Bioorganic & Medicinal Chemistry|October 2, 2020
Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugsMckayla Stevens, Chris Howe, Anne-Marie Ray, et al.Bioorganic & Medicinal Chemistry Letters|March 11, 2019
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive moleculesMckayla Stevens, Sanofar Abdeen, Nilshad Salim, et al.Journal of Medicinal Chemistry|November 6, 2018
Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureusTrent Kunkle, Sanofar Abdeen, Nilshad Salim, et al.Bioorganic & Medicinal Chemistry Letters|May 4, 2019
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infectionsAlex Washburn, Sanofar Abdeen, Yulia Ovechkina, et al.Journal of Medicinal Chemistry|August 1, 2018
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA)Sanofar Abdeen, Trent Kunkle, Nilshad Salim, et al.The Journal of Biological Chemistry|February 24, 2019
Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamicsChun-Xiang Wu, Jingling Liao, Yangshin Park, et al.Mbio|January 13, 2021
Functional Differences between E. coli and ESKAPE Pathogen GroES/GroELJared Sivinski, Andrew J Ambrose, Iliya Panfilenko, et al.Parkinsonism & Related Disorders|July 6, 2021
A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson's diseaseChristina Fevga, Yangshin Park, Ebba Lohmann, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 24, 2022
Allosteric differences dictate GroEL complementation of E. coliJared Sivinski, Duc Ngo, Christopher J Zerio, et al.Pageof 2