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Journal of Agricultural and Food Chemistry|September 18, 2024
Target Fishing Reveals a Novel Mechanism of N-Acylamino Saccharin Derivatives Targeting Glyceraldehyde-3-Phosphate Dehydrogenase toward Cyanobacterial Blooms ControlHongxuan Cao, Zeyue Huang, Zheng Liu, et al.Journal of Medicinal Chemistry|November 20, 2025
Fragment-Based Screening of NSD2-PWWP1 Identifies Novel Covalent Allosteric Ligands That Diminish Methyllysine and DNA Binding Abilities of NSD2Yunyuan Huang, Yanxi Li, Xin Chen, et al.Journal of Medicinal Chemistry|July 5, 2022
N-Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose ReductionWuqiang Wen, Hongxuan Cao, Yixiang Xu, et al.Journal of Medicinal Chemistry|February 24, 2026
Nitro-Diphenyl Ethers as Emerging Cysteine-Targeting Covalent Warheads Enable Identification of Novel Target LDLRAP1 for Anticoronaviral ActivityZeyue Huang, Xiuqi Hu, Zheng Liu, et al.Journal of Medicinal Chemistry|March 16, 2026
Crystallographic Study Reveals a Cryptic Allosteric Site of FBPase by Sulfonylurea Inhibitors toward T2DM TreatmentZeyue Huang, Xiuqi Hu, Zheng Liu, et al.Journal of Medicinal Chemistry|January 31, 2022
Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of CandidiasisWuqiang Wen, Hongxuan Cao, Yunyuan Huang, et al.Journal of Chemical Information and Modeling|June 26, 2012
Structure-based design and screen of novel inhibitors for class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniaeDing Li, Jie Gui, Yongjian Li, et al.Journal of Medicinal Chemistry|May 8, 2020
Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose ReductionYunyuan Huang, Yixiang Xu, Rongrong Song, et al.European Journal of Medicinal Chemistry|March 14, 2025
Rapid discovery of pseudorabies virus inhibitors repurposed from the antimicrobial agent ciprofloxacinLin Wei, Yun You, Yang Hu, et al.Nature Communications|March 4, 2026
Inhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an antifungal strategyHongxuan Cao, Jie Tu, Jiahui Chen, et al.Pageof 5