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Molecular Therapy. Advances|June 3, 2026
Efficient and safe lung gene delivery using AAV6.2FF in neonatal pigs demonstrates pediatric translational potentialNicole Zielinska, Erin L Howard, Cici Yang, et al.Viruses|January 21, 2023
Generation and Characterization of a SARS-CoV-2-Susceptible Mouse Model Using Adeno-Associated Virus (AAV6.2FF)-Mediated Respiratory Delivery of the Human ACE2 GeneNikesh Tailor, Bryce M Warner, Bryan D Griffin, et al.Gene Therapy|February 2, 2023
Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxisAmira D Rghei, Jacob G E Yates, Jordyn A Lopes, et al.Gene Therapy|April 27, 2024
AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumoniaJordyn A Lopes, Nicole E Garnier, Yanlong Pei, et al.Nature Communications|August 9, 2020
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiencyMartin H Kang, Laura P van Lieshout, Liqun Xu, et al.Journal of Virology|January 16, 2025
Vaccination against SARS-CoV-2 provides low-level cross-protection against common cold coronaviruses in mouse and non-human primate animal modelsMaedeh Naghibosadat, George Giorgi Babuadze, Yanlong Pei, et al.Biomedicines|September 28, 2021
Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal ModelsAmira D Rghei, Laura P van Lieshout, Benjamin M McLeod, et al.Biomedicines|February 25, 2022
AAV-Vectored Expression of the Vascular Normalizing Agents 3TSR and Fc3TSR, and the Anti-Angiogenic Bevacizumab Extends Survival in a Murine Model of End-Stage Epithelial Ovarian CarcinomaAshley A Stegelmeier, Lisa A Santry, Matthew M Guilleman, et al.Vaccines|April 27, 2024
Mucosal Vaccination with a Newcastle Disease Virus-Vectored Vaccine Reduces Viral Loads in SARS-CoV-2-Infected Cynomolgus MacaquesBryce M Warner, Mable Chan, Nikesh Tailor, et al.Gene Therapy|July 1, 2026
Improving the precision of AAV lung gene therapy for SP-B deficiency using computationally derived lung-specific promotersNicole Zielinska, Erin L Howard, Brenna A Y Stevens, et al.Pageof 5