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Cellular Signalling|November 16, 2024
Regulation and functions of the DLC family of RhoGAP proteins: Implications for development and cancerYannick Frey, Cristiana Lungu, Monilola A Olayioye
Scientific Reports|March 24, 2022
Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7Yannick Frey, Mirita Franz-Wachtel, Boris Macek, et al.
Iscience|September 19, 2025
PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasisElena Gutiérrez-Galindo, Katharina Jursik, Yannick Frey, et al.
The Journal of Biological Chemistry|July 27, 2018
The tumor suppressor protein DLC1 maintains protein kinase D activity and Golgi secretory functionAntje Jensch, Yannick Frey, Katharina Bitschar, et al.
Journal of Cell Science|May 12, 2019
DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranesBettina Noll, David Benz, Yannick Frey, et al.
Iscience|July 18, 2024
Regulation of the DLC3 tumor suppressor by a novel phosphoswitchYannick Frey, Cristiana Lungu, Florian Meyer, et al.
The EMBO Journal|August 19, 2024
The unfolded protein response regulates ER exit sites via SNRPB-dependent RNA splicing and contributes to bone developmentMuhammad Zahoor, Yanchen Dong, Marco Preussner, et al.
Research Square|July 10, 2026
Mechanosensing at the endoplasmic reticulum by IRE1Hesso Farhan, Michaela Mayr, Luiz Garcia-Souza, et al.
Neoplasia (New York, N.Y.)|November 29, 2025
Filamin a binds deleted in liver cancer 1 (DLC1) to promote its tumor suppressor activity and inhibit the SRF coactivator MRTF-AMichael Sergeev, Melanie A Meier, Petra Wohlleben, et al.
Leukemia|July 9, 2025
Targeting proteostasis in multiple myeloma through inhibition of LTKThea Kristin Våtsveen, Mariaserena Giliberto, Valgerdur Bjornsdottir, et al.
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