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Methods in Enzymology|May 7, 2022
Co-expression of recombinant RIPK3:MLKL complexes using the baculovirus-insect cell systemCheree Fitzgibbon, Yanxiang Meng, James M Murphy
Cell Death and Differentiation|January 19, 2021
The regulation of necroptosis by post-translational modificationsYanxiang Meng, Jarrod J Sandow, Peter E Czabotar, et al.
The Journal of Biological Chemistry|January 25, 2020
Structure-function analyses of alkylhydroperoxidase D from Streptococcus pneumoniae reveal an unusual three-cysteine active site architectureYanxiang Meng, Campbell R Sheen, Nicholas J Magon, et al.
The Biochemical Journal|August 13, 2024
Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activationSarah E Garnish, Christopher R Horne, Yanxiang Meng, et al.
Cell Death & Disease|June 23, 2022
Human RIPK3 C-lobe phosphorylation is essential for necroptotic signalingYanxiang Meng, Christopher R Horne, Andre L Samson, et al.
Biochemistry|June 2, 2020
Structure-Function Studies of the Antibiotic Target l,l-Diaminopimelate Aminotransferase from Verrucomicrobium spinosum Reveal an Unusual Oligomeric StructureAnthony W Weatherhead, Jennifer M Crowther, Christopher R Horne, et al.
Nature Communications|November 23, 2021
Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosisYanxiang Meng, Katherine A Davies, Cheree Fitzgibbon, et al.
Nature Communications|October 26, 2023
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerizationYanxiang Meng, Sarah E Garnish, Katherine A Davies, et al.
Nature Communications|April 14, 2021
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosisSarah E Garnish, Yanxiang Meng, Akiko Koide, et al.
Gastroenterology|August 29, 2022
Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver PathologiesSimon P Preston, Michael D Stutz, Cody C Allison, et al.
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