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Acta Pharmaceutica Sinica. B
|
July 19, 2024
Design and optimization of piperidine-substituted thiophene[3,2-<i>d</i>]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profiles
Yanying Sun, Zhenzhen Zhou, Zhongling Shi, et al.
ACS Infectious Diseases
|
July 4, 2020
Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs
Dongwei Kang, Yanying Sun, N Arul Murugan, et al.
European Journal of Medicinal Chemistry
|
August 21, 2024
Discovery of potent HIV-1 NNRTIs by CuAAC click-chemistry-based miniaturized synthesis, rapid screening and structure optimization
Lanlan Jing, Gaochan Wu, Fabao Zhao, et al.
Journal of Medicinal Chemistry
|
January 21, 2022
Development of Novel Dihydrofuro[3,4-<i>d</i>]pyrimidine Derivatives as HIV-1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C
Dongwei Kang, Yanying Sun, Da Feng, et al.
Journal of Medicinal Chemistry
|
April 13, 2024
Discovery of Novel Aryl Triazolone Dihydropyridines (ATDPs) Targeting Highly Conserved Residue W229 as Promising HIV-1 NNRTIs
Yanying Sun, Zhenzhen Zhou, Na Wang, et al.
Acta Pharmaceutica Sinica. B
|
June 13, 2020
Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-<i>d</i>]pyrimidine derivatives as potent HIV-1 NNRTIs
Dongwei Kang, Da Feng, Tiziana Ginex, et al.
European Journal of Medicinal Chemistry
|
November 29, 2022
Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs: Crystallographic overlay-based molecular design, synthesis, and biological evaluation
Da Feng, Hao Lin, Liyang Jiang, et al.
Journal of Medicinal Chemistry
|
November 21, 2022
Lead Optimization and Avoidance of Metabolic-perturbing Motif Developing Novel Diarylpyrimidines as Potent HIV-1 NNRTIs
Yanying Sun, Zhenzhen Zhou, Da Feng, et al.
Journal of Medicinal Chemistry
|
March 18, 2021
2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 NNRTIs: Rational Design, Synthesis, Activity Evaluation, and Crystallographic Studies
Dongwei Kang, Francesc X Ruiz, Yanying Sun, et al.
Journal of Medicinal Chemistry
|
January 15, 2020
Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel
Dongwei Kang, F Xavier Ruiz, Da Feng, et al.
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of 4
Search research articles
Search
Showing results (21-30 of 35) with videos related to
Sort By:
Page
of 4
Acta Pharmaceutica Sinica. B
|
July 19, 2024
Design and optimization of piperidine-substituted thiophene[3,2-<i>d</i>]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profiles
Yanying Sun, Zhenzhen Zhou, Zhongling Shi, et al.
ACS Infectious Diseases
|
July 4, 2020
Structure-Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs
Dongwei Kang, Yanying Sun, N Arul Murugan, et al.
European Journal of Medicinal Chemistry
|
August 21, 2024
Discovery of potent HIV-1 NNRTIs by CuAAC click-chemistry-based miniaturized synthesis, rapid screening and structure optimization
Lanlan Jing, Gaochan Wu, Fabao Zhao, et al.
Journal of Medicinal Chemistry
|
January 21, 2022
Development of Novel Dihydrofuro[3,4-<i>d</i>]pyrimidine Derivatives as HIV-1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C
Dongwei Kang, Yanying Sun, Da Feng, et al.
Journal of Medicinal Chemistry
|
April 13, 2024
Discovery of Novel Aryl Triazolone Dihydropyridines (ATDPs) Targeting Highly Conserved Residue W229 as Promising HIV-1 NNRTIs
Yanying Sun, Zhenzhen Zhou, Na Wang, et al.
Acta Pharmaceutica Sinica. B
|
June 13, 2020
Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-<i>d</i>]pyrimidine derivatives as potent HIV-1 NNRTIs
Dongwei Kang, Da Feng, Tiziana Ginex, et al.
European Journal of Medicinal Chemistry
|
November 29, 2022
Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs: Crystallographic overlay-based molecular design, synthesis, and biological evaluation
Da Feng, Hao Lin, Liyang Jiang, et al.
Journal of Medicinal Chemistry
|
November 21, 2022
Lead Optimization and Avoidance of Metabolic-perturbing Motif Developing Novel Diarylpyrimidines as Potent HIV-1 NNRTIs
Yanying Sun, Zhenzhen Zhou, Da Feng, et al.
Journal of Medicinal Chemistry
|
March 18, 2021
2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 NNRTIs: Rational Design, Synthesis, Activity Evaluation, and Crystallographic Studies
Dongwei Kang, Francesc X Ruiz, Yanying Sun, et al.
Journal of Medicinal Chemistry
|
January 15, 2020
Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel
Dongwei Kang, F Xavier Ruiz, Da Feng, et al.
Page
of 4