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Bioorganic & Medicinal Chemistry|March 25, 2014
Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallographyYasushi Amano, Tomohiko Yamaguchi, Eiki Tanabe
Bioorganic & Medicinal Chemistry|April 12, 2015
Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screeningYasushi Amano, Eiki Tanabe, Tomohiko Yamaguchi
Acta Crystallographica. Section D, Biological Crystallography|April 8, 2015
Structures of complexes of type 5 17β-hydroxysteroid dehydrogenase with structurally diverse inhibitors: insights into the conformational changes upon inhibitor bindingYasushi Amano, Tomohiko Yamaguchi, Tatsuya Niimi, et al.
Expert Opinion on Drug Discovery|March 14, 2013
Advances in fragment-based drug discovery platformsMasaya Orita, Masaichi Warizaya, Yasushi Amano, et al.
Methods in Enzymology|March 5, 2011
Lead generation and examples opinion regarding how to follow up hitsMasaya Orita, Kazuki Ohno, Masaichi Warizaya, et al.
Hypertension Research : Official Journal of the Japanese Society of Hypertension|February 24, 2012
Structural basis for telmisartan-mediated partial activation of PPAR gammaYasushi Amano, Tomohiko Yamaguchi, Kazuki Ohno, et al.
Bioorganic & Medicinal Chemistry|May 20, 2014
Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stabilityAyaka Chino, Naoyuki Masuda, Yasushi Amano, et al.
Acta Crystallographica. Section D, Biological Crystallography|September 2, 2015
Structural insights into the novel inhibition mechanism of Trypanosoma cruzi spermidine synthaseYasushi Amano, Ichiji Namatame, Yukihiro Tateishi, et al.
Oncotarget|November 7, 2019
Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cellsTatsuya Kawase, Taisuke Nakazawa, Tomohiro Eguchi, et al.
Bioorganic & Medicinal Chemistry|November 19, 2013
Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibitionWataru Hamaguchi, Naoyuki Masuda, Mai Isomura, et al.
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