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Yechun Xu

Showing results (141-150 of 154) with videos related to

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Nature Communications|October 13, 2023
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvirXiangrui Jiang, Haixia Su, Weijuan Shang, et al.
Journal of the American Chemical Society|November 22, 2024
Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein InhibitorsXudong Wang, Liwei Xiong, Ying Zhu, et al.
Journal of Medicinal Chemistry|April 26, 2019
Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial HypertensionZhen Wang, Xiangrui Jiang, Xianglei Zhang, et al.
Cell Discovery|March 22, 2018
Crystal structure of the human 5-HT<sub>1B</sub> serotonin receptor bound to an inverse agonistWanchao Yin, X Edward Zhou, Dehua Yang, et al.
Science (New York, N.Y.)|May 3, 2020
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivirWanchao Yin, Chunyou Mao, Xiaodong Luan, et al.
Frontiers in Medicine|December 14, 2023
Repurposing of Rutan showed effective treatment for COVID-19 diseaseShavkat I Salikhov, Ibrokhim Y Abdurakhmonov, Yuliya I Oshchepkova, et al.
Journal of Medicinal Chemistry|June 16, 2022
Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure DeterminationThanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger, et al.
Cell Research|February 6, 2013
Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14Li-Hua Zhao, X Edward Zhou, Zhong-Shan Wu, et al.
Science (New York, N.Y.)|April 24, 2020
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main proteaseWenhao Dai, Bing Zhang, Xia-Ming Jiang, et al.
Nature|April 10, 2020
Structure of M<sup>pro</sup> from SARS-CoV-2 and discovery of its inhibitorsZhenming Jin, Xiaoyu Du, Yechun Xu, et al.
Pageof 16

Showing results (141-150 of 154) with videos related to

Sort By:
Pageof 16
Nature Communications|October 13, 2023
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvirXiangrui Jiang, Haixia Su, Weijuan Shang, et al.
Journal of the American Chemical Society|November 22, 2024
Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein InhibitorsXudong Wang, Liwei Xiong, Ying Zhu, et al.
Journal of Medicinal Chemistry|April 26, 2019
Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial HypertensionZhen Wang, Xiangrui Jiang, Xianglei Zhang, et al.
Cell Discovery|March 22, 2018
Crystal structure of the human 5-HT<sub>1B</sub> serotonin receptor bound to an inverse agonistWanchao Yin, X Edward Zhou, Dehua Yang, et al.
Science (New York, N.Y.)|May 3, 2020
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivirWanchao Yin, Chunyou Mao, Xiaodong Luan, et al.
Frontiers in Medicine|December 14, 2023
Repurposing of Rutan showed effective treatment for COVID-19 diseaseShavkat I Salikhov, Ibrokhim Y Abdurakhmonov, Yuliya I Oshchepkova, et al.
Journal of Medicinal Chemistry|June 16, 2022
Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure DeterminationThanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger, et al.
Cell Research|February 6, 2013
Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14Li-Hua Zhao, X Edward Zhou, Zhong-Shan Wu, et al.
Science (New York, N.Y.)|April 24, 2020
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main proteaseWenhao Dai, Bing Zhang, Xia-Ming Jiang, et al.
Nature|April 10, 2020
Structure of M<sup>pro</sup> from SARS-CoV-2 and discovery of its inhibitorsZhenming Jin, Xiaoyu Du, Yechun Xu, et al.
Pageof 16