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Science Translational Medicine|November 21, 2014
A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycinYifeng Xia, Yi-Liang Liu, Yonghua Xie, et al.Antimicrobial Agents and Chemotherapy|February 5, 2014
Dronedarone, an amiodarone analog with improved anti-Leishmania mexicana efficacyGustavo Benaim, Paola Casanova, Vanessa Hernandez-Rodriguez, et al.Proceedings of the National Academy of Sciences of the United States of America|March 7, 2012
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activityJoo Hwan No, Fernando de Macedo Dossin, Yonghui Zhang, et al.ACS Medicinal Chemistry Letters|April 24, 2013
Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid BiosynthesisYonghui Zhang, Wei Zhu, Yi-Liang Liu, et al.Journal of Medicinal Chemistry|May 22, 2009
Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic resultsYongcheng Song, Chia-I Liu, Fu-Yang Lin, et al.Chembiochem : a European Journal of Chemical Biology|January 17, 2013
Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureusFeifei Ren, Xinxin Feng, Tzu-Ping Ko, et al.ACS Medicinal Chemistry Letters|June 5, 2012
HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid BiosynthesisYonghui Zhang, Fu-Yang Lin, Kai Li, et al.Communications Biology|May 22, 2023
Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respirationJu-Yi Hsieh, Kun-Chi Chen, Chun-Hsiung Wang, et al.Iscience|February 8, 2021
Single nucleotide variants lead to dysregulation of the human mitochondrial NAD(P)+-dependent malic enzymeJu-Yi Hsieh, Hao-Ping Yang, Sunil Kumar Tewary, et al.Proceedings of the National Academy of Sciences of the United States of America|December 19, 2012
Antibacterial drug leads targeting isoprenoid biosynthesisWei Zhu, Yonghui Zhang, William Sinko, et al.Pageof 5